arhgef12 protein (Takifugu rubripes) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

arhgef12

Rho guanine nucleotide exchange factor (GEF) 12a. (1437 aa)

Predicted Functional Partners:

LOC101071876

0.974

gna12

0.974

LOC101065558

0.974

LOC101076147

0.962

LOC101070117

0.962

LOC101064166

0.962

LOC101066462

0.936

mras

0.922

LOC101069736

0.921

hras

0.921

Your Current Organism:

Takifugu rubripes

NCBI taxonomy Id: 31033
Other names: Fugu rubripes, Sphaeroides rubripes, T. rubripes, Tetraodon rubripes, tiger puffer, torafugu

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
LOC101064166	LOC101065558	ENSTRUP00000062293	ENSTRUP00000046184	Uncharacterized protein.	Uncharacterized protein.	0.538
LOC101064166	LOC101066462	ENSTRUP00000062293	ENSTRUP00000069148	Uncharacterized protein.	Rho guanine nucleotide exchange factor (GEF) 7b.	0.421
LOC101064166	LOC101070117	ENSTRUP00000062293	ENSTRUP00000051209	Uncharacterized protein.	Ras homolog gene family, member Aa.	0.900
LOC101064166	LOC101071876	ENSTRUP00000062293	ENSTRUP00000028944	Uncharacterized protein.	Guanine nucleotide binding protein (G protein), alpha 13b.	0.538
LOC101064166	LOC101076147	ENSTRUP00000062293	ENSTRUP00000027633	Uncharacterized protein.	Uncharacterized protein.	0.900
LOC101064166	arhgef12	ENSTRUP00000062293	ENSTRUP00000038066	Uncharacterized protein.	Rho guanine nucleotide exchange factor (GEF) 12a.	0.962
LOC101064166	gna12	ENSTRUP00000062293	ENSTRUP00000029080	Uncharacterized protein.	G protein subunit alpha 12.	0.538
LOC101065558	LOC101064166	ENSTRUP00000046184	ENSTRUP00000062293	Uncharacterized protein.	Uncharacterized protein.	0.538
LOC101065558	LOC101070117	ENSTRUP00000046184	ENSTRUP00000051209	Uncharacterized protein.	Ras homolog gene family, member Aa.	0.538
LOC101065558	LOC101071876	ENSTRUP00000046184	ENSTRUP00000028944	Uncharacterized protein.	Guanine nucleotide binding protein (G protein), alpha 13b.	0.900
LOC101065558	LOC101076147	ENSTRUP00000046184	ENSTRUP00000027633	Uncharacterized protein.	Uncharacterized protein.	0.538
LOC101065558	arhgef12	ENSTRUP00000046184	ENSTRUP00000038066	Uncharacterized protein.	Rho guanine nucleotide exchange factor (GEF) 12a.	0.974
LOC101065558	gna12	ENSTRUP00000046184	ENSTRUP00000029080	Uncharacterized protein.	G protein subunit alpha 12.	0.901
LOC101066462	LOC101064166	ENSTRUP00000069148	ENSTRUP00000062293	Rho guanine nucleotide exchange factor (GEF) 7b.	Uncharacterized protein.	0.421
LOC101066462	LOC101070117	ENSTRUP00000069148	ENSTRUP00000051209	Rho guanine nucleotide exchange factor (GEF) 7b.	Ras homolog gene family, member Aa.	0.421
LOC101066462	LOC101076147	ENSTRUP00000069148	ENSTRUP00000027633	Rho guanine nucleotide exchange factor (GEF) 7b.	Uncharacterized protein.	0.421
LOC101066462	arhgef12	ENSTRUP00000069148	ENSTRUP00000038066	Rho guanine nucleotide exchange factor (GEF) 7b.	Rho guanine nucleotide exchange factor (GEF) 12a.	0.936
LOC101069736	arhgef12	ENSTRUP00000016293	ENSTRUP00000038066	Zgc:55558.	Rho guanine nucleotide exchange factor (GEF) 12a.	0.921
LOC101069736	hras	ENSTRUP00000016293	ENSTRUP00000052118	Zgc:55558.	HRas proto-oncogene, GTPase a.	0.910
LOC101070117	LOC101064166	ENSTRUP00000051209	ENSTRUP00000062293	Ras homolog gene family, member Aa.	Uncharacterized protein.	0.900