STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
kitMast/stem cell growth factor receptor Kit; Tyrosine-protein kinase that acts as cell-surface receptor for the cytokine kitlg/scf and plays an essential role in the regulation of cell survival and proliferation, hematopoiesis, stem cell maintenance, gametogenesis, mast cell development, migration and function, and in melanogenesis. (991 aa)    
Predicted Functional Partners:
scf
Uncharacterized protein.
   
 0.987
hras
HRas proto-oncogene, GTPase a.
   
 0.934
LOC101068411
Uncharacterized protein.
     
 0.934
LOC101069736
Zgc:55558.
   
 0.933
kras
V-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog.
   
 0.933
LOC101078652
KIT proto-oncogene, receptor tyrosine kinase b.
  
  
0.904
il34
Uncharacterized protein.
   
 0.879
grb2
Growth factor receptor-bound protein 2b.
   
 0.875
LOC101061204
Uncharacterized protein.
   
 0.875
LOC101076257
Colony stimulating factor 1b (macrophage).
   
 0.861
Your Current Organism:
Takifugu rubripes
NCBI taxonomy Id: 31033
Other names: Fugu rubripes, Sphaeroides rubripes, T. rubripes, Tetraodon rubripes, tiger puffer, torafugu
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.