STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
uacaUveal autoantigen with coiled-coil domains and ankyrin repeats b. (1386 aa)    
Predicted Functional Partners:
casp9
Caspase 9, apoptosis-related cysteine peptidase; Belongs to the peptidase C14A family.
    
 0.587
vcp
Valosin containing protein; Belongs to the AAA ATPase family.
    
 0.580
apaf1
Apoptotic protease-activating factor 1; Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP.
    
 0.541
tmem59
Transmembrane protein 59.
    
  0.530
nsfl1c
NSFL1 (p97) cofactor (p47).
    
  0.527
rhoq
Ras homolog family member Q.
   
  0.515
ENSTRUP00000075806
Rho-related GTP-binding protein RhoQ-like.
   
  0.515
spata5l1
Spermatogenesis associated 5-like 1.
    
 0.511
SPATA5
ATPase family protein 2 homolog.
    
 0.511
mtr
Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
   
 
  0.508
Your Current Organism:
Takifugu rubripes
NCBI taxonomy Id: 31033
Other names: Fugu rubripes, Sphaeroides rubripes, T. rubripes, Tetraodon rubripes, tiger puffer, torafugu
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