node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
GET1 | LOC101062737 | ENSTRUP00000003017 | ENSTRUP00000062804 | Guided entry of tail-anchored proteins factor 1. | Ubiquitin-like domain-containing protein. | 0.497 |
GET1 | RAD23B | ENSTRUP00000003017 | ENSTRUP00000023298 | Guided entry of tail-anchored proteins factor 1. | RAD23 homolog B, nucleotide excision repair protein. | 0.427 |
GET1 | Sec61b | ENSTRUP00000003017 | ENSTRUP00000028690 | Guided entry of tail-anchored proteins factor 1. | Uncharacterized protein. | 0.759 |
GET1 | get3 | ENSTRUP00000003017 | ENSTRUP00000016528 | Guided entry of tail-anchored proteins factor 1. | ATPase ASNA1; ATPase required for the post-translational delivery of tail- anchored (TA) proteins to the endoplasmic reticulum. Recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol. This complex then targets to the endoplasmic reticulum by membrane-bound receptors, where the tail-anchored protein is released for insertion. This process is regulated by ATP binding and hydrolysis. ATP binding drives the homodimer towards the closed dimer state, facilitating recognition of newly synthesized TA membrane proteins. ATP hydrolysis is required for insertion. [...] | 0.993 |
GET1 | get4 | ENSTRUP00000003017 | ENSTRUP00000075437 | Guided entry of tail-anchored proteins factor 1. | Golgi to ER traffic protein 4 homolog; As part of a cytosolic protein quality control complex, the bag6/bat3 complex, maintains misfolded and hydrophobic patches- containing proteins in a soluble state and participates to their proper delivery to the endoplasmic reticulum or alternatively can promote their sorting to the proteasome where they undergo degradation. The bag6/bat3 complex is involved in the post-translational delivery of tail-anchored/type II transmembrane proteins to the endoplasmic reticulum membrane. Similarly, the bag6/bat3 complex also functions as a sorting platform [...] | 0.731 |
GET1 | rad23a | ENSTRUP00000003017 | ENSTRUP00000084012 | Guided entry of tail-anchored proteins factor 1. | RAD23 homolog A, nucleotide excision repair protein a. | 0.427 |
GET1 | sgta | ENSTRUP00000003017 | ENSTRUP00000029013 | Guided entry of tail-anchored proteins factor 1. | Small glutamine-rich tetratricopeptide repeat (TPR)-containing, alpha. | 0.630 |
GET1 | sgtb | ENSTRUP00000003017 | ENSTRUP00000069166 | Guided entry of tail-anchored proteins factor 1. | Small glutamine-rich tetratricopeptide repeat (TPR)-containing, beta. | 0.630 |
GET1 | ttc33 | ENSTRUP00000003017 | ENSTRUP00000047209 | Guided entry of tail-anchored proteins factor 1. | Tetratricopeptide repeat domain 33. | 0.498 |
LOC101062737 | GET1 | ENSTRUP00000062804 | ENSTRUP00000003017 | Ubiquitin-like domain-containing protein. | Guided entry of tail-anchored proteins factor 1. | 0.497 |
LOC101062737 | RAD23B | ENSTRUP00000062804 | ENSTRUP00000023298 | Ubiquitin-like domain-containing protein. | RAD23 homolog B, nucleotide excision repair protein. | 0.750 |
LOC101062737 | Sec61b | ENSTRUP00000062804 | ENSTRUP00000028690 | Ubiquitin-like domain-containing protein. | Uncharacterized protein. | 0.573 |
LOC101062737 | bag6 | ENSTRUP00000062804 | ENSTRUP00000014707 | Ubiquitin-like domain-containing protein. | BCL2 associated athanogene 6. | 0.963 |
LOC101062737 | get3 | ENSTRUP00000062804 | ENSTRUP00000016528 | Ubiquitin-like domain-containing protein. | ATPase ASNA1; ATPase required for the post-translational delivery of tail- anchored (TA) proteins to the endoplasmic reticulum. Recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol. This complex then targets to the endoplasmic reticulum by membrane-bound receptors, where the tail-anchored protein is released for insertion. This process is regulated by ATP binding and hydrolysis. ATP binding drives the homodimer towards the closed dimer state, facilitating recognition of newly synthesized TA membrane proteins. ATP hydrolysis is required for insertion. [...] | 0.818 |
LOC101062737 | get4 | ENSTRUP00000062804 | ENSTRUP00000075437 | Ubiquitin-like domain-containing protein. | Golgi to ER traffic protein 4 homolog; As part of a cytosolic protein quality control complex, the bag6/bat3 complex, maintains misfolded and hydrophobic patches- containing proteins in a soluble state and participates to their proper delivery to the endoplasmic reticulum or alternatively can promote their sorting to the proteasome where they undergo degradation. The bag6/bat3 complex is involved in the post-translational delivery of tail-anchored/type II transmembrane proteins to the endoplasmic reticulum membrane. Similarly, the bag6/bat3 complex also functions as a sorting platform [...] | 0.893 |
LOC101062737 | rad23a | ENSTRUP00000062804 | ENSTRUP00000084012 | Ubiquitin-like domain-containing protein. | RAD23 homolog A, nucleotide excision repair protein a. | 0.750 |
LOC101062737 | sgta | ENSTRUP00000062804 | ENSTRUP00000029013 | Ubiquitin-like domain-containing protein. | Small glutamine-rich tetratricopeptide repeat (TPR)-containing, alpha. | 0.755 |
LOC101062737 | sgtb | ENSTRUP00000062804 | ENSTRUP00000069166 | Ubiquitin-like domain-containing protein. | Small glutamine-rich tetratricopeptide repeat (TPR)-containing, beta. | 0.742 |
RAD23B | GET1 | ENSTRUP00000023298 | ENSTRUP00000003017 | RAD23 homolog B, nucleotide excision repair protein. | Guided entry of tail-anchored proteins factor 1. | 0.427 |
RAD23B | LOC101062737 | ENSTRUP00000023298 | ENSTRUP00000062804 | RAD23 homolog B, nucleotide excision repair protein. | Ubiquitin-like domain-containing protein. | 0.750 |