STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LOC101080224Notch receptor 2. (2500 aa)    
Predicted Functional Partners:
rbpj
Recombination signal binding protein for immunoglobulin kappa J region.
    
 0.984
jag1
Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.
   
0.959
jag2
Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.
   
0.953
rbpjl
Recombining binding protein suppressor of hairless-like protein isoform X1.
    
 0.948
numb
NUMB endocytic adaptor protein.
   
 0.943
H2TJ00_TAKRU
MNNL domain-containing protein.
     
 0.942
LOC101072040
NUMB like endocytic adaptor protein.
   
 0.942
NCSTN
Nicastrin.
    
 0.929
LOC101077303
Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family.
    
 0.924
LOC101073848
MFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase.
    
 0.922
Your Current Organism:
Takifugu rubripes
NCBI taxonomy Id: 31033
Other names: Fugu rubripes, Sphaeroides rubripes, T. rubripes, Tetraodon rubripes, tiger puffer, torafugu
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.