STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LOC101074076Sodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. (1963 aa)    
Predicted Functional Partners:
LOC101077821
Sodium channel, voltage-gated, type I, beta a.
   
 0.787
LOC101064058
Ig-like domain-containing protein.
    
 0.732
wdr35
WD repeat-containing protein 35.
    
 0.701
IFT122
Intraflagellar transport 122.
   
 0.692
wdr19
WD repeat domain 19.
    
 0.685
ift140
Intraflagellar transport 140 homolog (Chlamydomonas).
    
 0.684
scn3b
Sodium channel, voltage-gated, type III, beta.
   
 0.638
scn1b
Sodium channel, voltage-gated, type I, beta b.
   
 0.631
LOC101068022
Myelin protein zero-like 2b.
   
 0.557
nfasc
Neurofascin homolog (chicken) a.
   
 0.534
Your Current Organism:
Takifugu rubripes
NCBI taxonomy Id: 31033
Other names: Fugu rubripes, Sphaeroides rubripes, T. rubripes, Tetraodon rubripes, tiger puffer, torafugu
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