pcna protein (Takifugu rubripes) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

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textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Current Organism:

Takifugu rubripes

NCBI taxonomy Id: 31033
Other names: Fugu rubripes, Sphaeroides rubripes, T. rubripes, Tetraodon rubripes, tiger puffer, torafugu

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structured XML interaction data, according to the 'PSI-MI' data standard

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSTRUP00000080931	mcm7	ENSTRUP00000080931	ENSTRUP00000084916	Ligase I, DNA, ATP-dependent.	DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...]	0.834
ENSTRUP00000080931	msh6	ENSTRUP00000080931	ENSTRUP00000034377	Ligase I, DNA, ATP-dependent.	DNA mismatch repair protein; Component of the post-replicative DNA mismatch repair system (MMR).	0.784
ENSTRUP00000080931	pcna	ENSTRUP00000080931	ENSTRUP00000052987	Ligase I, DNA, ATP-dependent.	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.	0.997
ENSTRUP00000080931	pold1	ENSTRUP00000080931	ENSTRUP00000068163	Ligase I, DNA, ATP-dependent.	DNA polymerase.	0.961
ENSTRUP00000080931	pold2	ENSTRUP00000080931	ENSTRUP00000013414	Ligase I, DNA, ATP-dependent.	Polymerase (DNA directed), delta 2, regulatory subunit.	0.810
ENSTRUP00000080931	rfc2	ENSTRUP00000080931	ENSTRUP00000024932	Ligase I, DNA, ATP-dependent.	Replication factor C (activator 1) 2.	0.864
ENSTRUP00000080931	rfc4	ENSTRUP00000080931	ENSTRUP00000013242	Ligase I, DNA, ATP-dependent.	Replication factor C (activator 1) 4.	0.961
ENSTRUP00000080931	rfc5	ENSTRUP00000080931	ENSTRUP00000086671	Ligase I, DNA, ATP-dependent.	Replication factor C (activator 1) 5.	0.862
dtl	msh6	ENSTRUP00000067730	ENSTRUP00000034377	Denticleless E3 ubiquitin protein ligase homolog (Drosophila).	DNA mismatch repair protein; Component of the post-replicative DNA mismatch repair system (MMR).	0.477
dtl	pcna	ENSTRUP00000067730	ENSTRUP00000052987	Denticleless E3 ubiquitin protein ligase homolog (Drosophila).	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.	0.995
dtl	pold1	ENSTRUP00000067730	ENSTRUP00000068163	Denticleless E3 ubiquitin protein ligase homolog (Drosophila).	DNA polymerase.	0.682
dtl	pold2	ENSTRUP00000067730	ENSTRUP00000013414	Denticleless E3 ubiquitin protein ligase homolog (Drosophila).	Polymerase (DNA directed), delta 2, regulatory subunit.	0.650
dtl	rfc2	ENSTRUP00000067730	ENSTRUP00000024932	Denticleless E3 ubiquitin protein ligase homolog (Drosophila).	Replication factor C (activator 1) 2.	0.736
dtl	rfc4	ENSTRUP00000067730	ENSTRUP00000013242	Denticleless E3 ubiquitin protein ligase homolog (Drosophila).	Replication factor C (activator 1) 4.	0.743
dtl	rfc5	ENSTRUP00000067730	ENSTRUP00000086671	Denticleless E3 ubiquitin protein ligase homolog (Drosophila).	Replication factor C (activator 1) 5.	0.670
dtl	usp1	ENSTRUP00000067730	ENSTRUP00000047357	Denticleless E3 ubiquitin protein ligase homolog (Drosophila).	Ubiquitin carboxyl-terminal hydrolase.	0.746
mcm7	ENSTRUP00000080931	ENSTRUP00000084916	ENSTRUP00000080931	DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...]	Ligase I, DNA, ATP-dependent.	0.834
mcm7	msh6	ENSTRUP00000084916	ENSTRUP00000034377	DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...]	DNA mismatch repair protein; Component of the post-replicative DNA mismatch repair system (MMR).	0.469
mcm7	pcna	ENSTRUP00000084916	ENSTRUP00000052987	DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...]	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.	0.997
mcm7	pold1	ENSTRUP00000084916	ENSTRUP00000068163	DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...]	DNA polymerase.	0.881