STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LOC101074989Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (95 aa)    
Predicted Functional Partners:
LOC101068314
Histone H3.
 
 
 0.850
ENSTRUP00000052153
Histone H3; Belongs to the histone H3 family.
 
 
 0.846
ENSTRUP00000049431
Histone H3; Belongs to the histone H3 family.
 
 
 0.845
ENSTRUP00000049880
Histone H3; Belongs to the histone H3 family.
 
 
 0.845
ENSTRUP00000077515
Histone H3; Belongs to the histone H3 family.
 
 
 0.845
H2T664_TAKRU
Histone H3; Belongs to the histone H3 family.
 
 
 0.842
H2V558_TAKRU
Histone H3; Belongs to the histone H3 family.
 
 
 0.842
LOC101063521
Histone H3; Belongs to the histone H3 family.
 
 
 0.839
ENSTRUP00000054961
Histone H3; Belongs to the histone H3 family.
 
 
 0.838
LOC101070924
Histone H3; Belongs to the histone H3 family.
 
 
 0.835
Your Current Organism:
Takifugu rubripes
NCBI taxonomy Id: 31033
Other names: Fugu rubripes, Sphaeroides rubripes, T. rubripes, Tetraodon rubripes, tiger puffer, torafugu
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