STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
btkTyrosine-protein kinase. (634 aa)    
Predicted Functional Partners:
ENSTRUP00000053105
Lymphocyte cytosolic protein 2a.
   
 0.785
plcg2
Phosphoinositide phospholipase C.
   
 0.695
blnk
B cell linker.
   
 0.685
syk
Tyrosine-protein kinase.
  
0.663
sos2
Son of sevenless homolog 2 (Drosophila).
    
 0.649
cd247
Uncharacterized protein.
   
 0.639
SOS1
SOS Ras/Rac guanine nucleotide exchange factor 1.
    
 0.636
grb2
Growth factor receptor-bound protein 2b.
   
0.628
zap70
Tyrosine-protein kinase.
  
0.619
ENSTRUP00000018134
GRB2 related adaptor protein 2a.
   
0.612
Your Current Organism:
Takifugu rubripes
NCBI taxonomy Id: 31033
Other names: Fugu rubripes, Sphaeroides rubripes, T. rubripes, Tetraodon rubripes, tiger puffer, torafugu
Server load: low (20%) [HD]