LOC101063424 protein (Takifugu rubripes) - STRING interaction network

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LOC101063424

Sulfotransferase; Belongs to the sulfotransferase 1 family. (355 aa)

Predicted Functional Partners:

hsd3b1

0.922

LOC101074542

0.912

LOC101069556

0.910

LOC115248714

0.910

LOC101066982

0.910

LOC101069124

0.908

LOC101063139

0.907

LOC101065551

0.906

cyp17a2

0.906

cyp17a1

0.906

Your Current Organism:

Takifugu rubripes

NCBI taxonomy Id: 31033
Other names: Fugu rubripes, Sphaeroides rubripes, T. rubripes, Tetraodon rubripes, tiger puffer, torafugu

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
LOC101063139	LOC101063424	ENSTRUP00000076139	ENSTRUP00000070429	Cholesterol side-chain cleavage enzyme, mitochondrial; A cytochrome P450 monooxygenase that catalyzes the side-chain hydroxylation and cleavage of cholesterol to pregnenolone, the precursor of most steroid hormones. Catalyzes three sequential oxidation reactions of cholesterol, namely the hydroxylation at C22 followed with the hydroxylation at C20 to yield 20R,22R- hydroxycholesterol that is further cleaved between C20 and C22 to yield the C21-steroid pregnenolone and 4-methylpentanal. Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate and reducing the se [...]	Sulfotransferase; Belongs to the sulfotransferase 1 family.	0.907
LOC101063139	LOC101065551	ENSTRUP00000076139	ENSTRUP00000024904	Cholesterol side-chain cleavage enzyme, mitochondrial; A cytochrome P450 monooxygenase that catalyzes the side-chain hydroxylation and cleavage of cholesterol to pregnenolone, the precursor of most steroid hormones. Catalyzes three sequential oxidation reactions of cholesterol, namely the hydroxylation at C22 followed with the hydroxylation at C20 to yield 20R,22R- hydroxycholesterol that is further cleaved between C20 and C22 to yield the C21-steroid pregnenolone and 4-methylpentanal. Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate and reducing the se [...]	Cytochrome P450, family 7, subfamily B, polypeptide 1; Belongs to the cytochrome P450 family.	0.937
LOC101063139	LOC101066982	ENSTRUP00000076139	ENSTRUP00000086933	Cholesterol side-chain cleavage enzyme, mitochondrial; A cytochrome P450 monooxygenase that catalyzes the side-chain hydroxylation and cleavage of cholesterol to pregnenolone, the precursor of most steroid hormones. Catalyzes three sequential oxidation reactions of cholesterol, namely the hydroxylation at C22 followed with the hydroxylation at C20 to yield 20R,22R- hydroxycholesterol that is further cleaved between C20 and C22 to yield the C21-steroid pregnenolone and 4-methylpentanal. Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate and reducing the se [...]	Steryl-sulfatase isoform X1.	0.904
LOC101063139	LOC101069556	ENSTRUP00000076139	ENSTRUP00000027981	Cholesterol side-chain cleavage enzyme, mitochondrial; A cytochrome P450 monooxygenase that catalyzes the side-chain hydroxylation and cleavage of cholesterol to pregnenolone, the precursor of most steroid hormones. Catalyzes three sequential oxidation reactions of cholesterol, namely the hydroxylation at C22 followed with the hydroxylation at C20 to yield 20R,22R- hydroxycholesterol that is further cleaved between C20 and C22 to yield the C21-steroid pregnenolone and 4-methylpentanal. Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate and reducing the se [...]	Cytochrome P450, family 7, subfamily A, polypeptide 1; Belongs to the cytochrome P450 family.	0.446
LOC101063139	LOC101074542	ENSTRUP00000076139	ENSTRUP00000054147	Cholesterol side-chain cleavage enzyme, mitochondrial; A cytochrome P450 monooxygenase that catalyzes the side-chain hydroxylation and cleavage of cholesterol to pregnenolone, the precursor of most steroid hormones. Catalyzes three sequential oxidation reactions of cholesterol, namely the hydroxylation at C22 followed with the hydroxylation at C20 to yield 20R,22R- hydroxycholesterol that is further cleaved between C20 and C22 to yield the C21-steroid pregnenolone and 4-methylpentanal. Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate and reducing the se [...]	Cytochrome P450, family 1, subfamily A; Belongs to the cytochrome P450 family.	0.439
LOC101063139	LOC115248714	ENSTRUP00000076139	ENSTRUP00000072562	Cholesterol side-chain cleavage enzyme, mitochondrial; A cytochrome P450 monooxygenase that catalyzes the side-chain hydroxylation and cleavage of cholesterol to pregnenolone, the precursor of most steroid hormones. Catalyzes three sequential oxidation reactions of cholesterol, namely the hydroxylation at C22 followed with the hydroxylation at C20 to yield 20R,22R- hydroxycholesterol that is further cleaved between C20 and C22 to yield the C21-steroid pregnenolone and 4-methylpentanal. Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate and reducing the se [...]	Steroid sulfatase (microsomal), isozyme S.	0.904
LOC101063139	cyp17a1	ENSTRUP00000076139	ENSTRUP00000075679	Cholesterol side-chain cleavage enzyme, mitochondrial; A cytochrome P450 monooxygenase that catalyzes the side-chain hydroxylation and cleavage of cholesterol to pregnenolone, the precursor of most steroid hormones. Catalyzes three sequential oxidation reactions of cholesterol, namely the hydroxylation at C22 followed with the hydroxylation at C20 to yield 20R,22R- hydroxycholesterol that is further cleaved between C20 and C22 to yield the C21-steroid pregnenolone and 4-methylpentanal. Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate and reducing the se [...]	Uncharacterized protein; Belongs to the cytochrome P450 family.	0.942
LOC101063139	cyp17a2	ENSTRUP00000076139	ENSTRUP00000026529	Cholesterol side-chain cleavage enzyme, mitochondrial; A cytochrome P450 monooxygenase that catalyzes the side-chain hydroxylation and cleavage of cholesterol to pregnenolone, the precursor of most steroid hormones. Catalyzes three sequential oxidation reactions of cholesterol, namely the hydroxylation at C22 followed with the hydroxylation at C20 to yield 20R,22R- hydroxycholesterol that is further cleaved between C20 and C22 to yield the C21-steroid pregnenolone and 4-methylpentanal. Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate and reducing the se [...]	Uncharacterized protein; Belongs to the cytochrome P450 family.	0.977
LOC101063139	hsd3b1	ENSTRUP00000076139	ENSTRUP00000040857	Cholesterol side-chain cleavage enzyme, mitochondrial; A cytochrome P450 monooxygenase that catalyzes the side-chain hydroxylation and cleavage of cholesterol to pregnenolone, the precursor of most steroid hormones. Catalyzes three sequential oxidation reactions of cholesterol, namely the hydroxylation at C22 followed with the hydroxylation at C20 to yield 20R,22R- hydroxycholesterol that is further cleaved between C20 and C22 to yield the C21-steroid pregnenolone and 4-methylpentanal. Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate and reducing the se [...]	Hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1; Belongs to the 3-beta-HSD family.	0.951
LOC101063424	LOC101063139	ENSTRUP00000070429	ENSTRUP00000076139	Sulfotransferase; Belongs to the sulfotransferase 1 family.	Cholesterol side-chain cleavage enzyme, mitochondrial; A cytochrome P450 monooxygenase that catalyzes the side-chain hydroxylation and cleavage of cholesterol to pregnenolone, the precursor of most steroid hormones. Catalyzes three sequential oxidation reactions of cholesterol, namely the hydroxylation at C22 followed with the hydroxylation at C20 to yield 20R,22R- hydroxycholesterol that is further cleaved between C20 and C22 to yield the C21-steroid pregnenolone and 4-methylpentanal. Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate and reducing the se [...]	0.907
LOC101063424	LOC101065551	ENSTRUP00000070429	ENSTRUP00000024904	Sulfotransferase; Belongs to the sulfotransferase 1 family.	Cytochrome P450, family 7, subfamily B, polypeptide 1; Belongs to the cytochrome P450 family.	0.906
LOC101063424	LOC101066982	ENSTRUP00000070429	ENSTRUP00000086933	Sulfotransferase; Belongs to the sulfotransferase 1 family.	Steryl-sulfatase isoform X1.	0.910
LOC101063424	LOC101069124	ENSTRUP00000070429	ENSTRUP00000017246	Sulfotransferase; Belongs to the sulfotransferase 1 family.	Uncharacterized protein; Belongs to the cytochrome P450 family.	0.908
LOC101063424	LOC101069556	ENSTRUP00000070429	ENSTRUP00000027981	Sulfotransferase; Belongs to the sulfotransferase 1 family.	Cytochrome P450, family 7, subfamily A, polypeptide 1; Belongs to the cytochrome P450 family.	0.910
LOC101063424	LOC101074542	ENSTRUP00000070429	ENSTRUP00000054147	Sulfotransferase; Belongs to the sulfotransferase 1 family.	Cytochrome P450, family 1, subfamily A; Belongs to the cytochrome P450 family.	0.912
LOC101063424	LOC115248714	ENSTRUP00000070429	ENSTRUP00000072562	Sulfotransferase; Belongs to the sulfotransferase 1 family.	Steroid sulfatase (microsomal), isozyme S.	0.910
LOC101063424	cyp17a1	ENSTRUP00000070429	ENSTRUP00000075679	Sulfotransferase; Belongs to the sulfotransferase 1 family.	Uncharacterized protein; Belongs to the cytochrome P450 family.	0.906
LOC101063424	cyp17a2	ENSTRUP00000070429	ENSTRUP00000026529	Sulfotransferase; Belongs to the sulfotransferase 1 family.	Uncharacterized protein; Belongs to the cytochrome P450 family.	0.906
LOC101063424	hsd3b1	ENSTRUP00000070429	ENSTRUP00000040857	Sulfotransferase; Belongs to the sulfotransferase 1 family.	Hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1; Belongs to the 3-beta-HSD family.	0.922
LOC101065551	LOC101063139	ENSTRUP00000024904	ENSTRUP00000076139	Cytochrome P450, family 7, subfamily B, polypeptide 1; Belongs to the cytochrome P450 family.	Cholesterol side-chain cleavage enzyme, mitochondrial; A cytochrome P450 monooxygenase that catalyzes the side-chain hydroxylation and cleavage of cholesterol to pregnenolone, the precursor of most steroid hormones. Catalyzes three sequential oxidation reactions of cholesterol, namely the hydroxylation at C22 followed with the hydroxylation at C20 to yield 20R,22R- hydroxycholesterol that is further cleaved between C20 and C22 to yield the C21-steroid pregnenolone and 4-methylpentanal. Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate and reducing the se [...]	0.937