STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
osgepProbable tRNA N6-adenosine threonylcarbamoyltransferase; Component of the EKC/KEOPS complex that is required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. The complex is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. OSGEP likely plays a direct catalytic role in this reaction, but requires other protein(s) of the complex to fulfill this activity. (360 aa)    
Predicted Functional Partners:
tp53rk
TP53 regulating kinase.
  
 0.995
acp1
LMWPc domain-containing protein.
    
 0.774
yrdc
YrdC N(6)-threonylcarbamoyltransferase domain containing.
  
 
 0.772
pip4p1-2
Type 1 phosphatidylinositol 4,5-bisphosphate 4-phosphatase isoform X1.
 
    
 0.752
LOC101062517
Si:ch211-153b23.4.
  
 
 0.751
LOC115252491
Uncharacterized LOC115252491.
  
 
 0.751
pip4p1
Phosphatidylinositol-4,5-bisphosphate 4-phosphatase; Catalyzes the hydrolysis of phosphatidylinositol-4,5- bisphosphate (PtdIns-4,5-P2) to phosphatidylinositol-4-phosphate (PtdIns-4-P).
 
    
 0.731
eprs1
Glutamyl-prolyl-tRNA synthetase.
  
 
 0.667
psmb1
Proteasome subunit beta.
 
    
 0.644
dcakd
Dephospho-CoA kinase domain containing.
    
 0.621
Your Current Organism:
Takifugu rubripes
NCBI taxonomy Id: 31033
Other names: Fugu rubripes, Sphaeroides rubripes, T. rubripes, Tetraodon rubripes, tiger puffer, torafugu
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