zap70 protein (Takifugu rubripes) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

zap70

Tyrosine-protein kinase. (631 aa)

Predicted Functional Partners:

cd247

0.953

cd3e

0.916

ENSTRUP00000053105

0.814

cd3g/d

0.808

tyrobp

0.782

ENSTRUP00000053545

0.775

ENSTRUP00000072102

0.775

plcg2

0.771

plcg1

0.771

LOC101065481

0.771

Your Current Organism:

Takifugu rubripes

NCBI taxonomy Id: 31033
Other names: Fugu rubripes, Sphaeroides rubripes, T. rubripes, Tetraodon rubripes, tiger puffer, torafugu

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSTRUP00000053105	ENSTRUP00000053545	ENSTRUP00000053105	ENSTRUP00000053545	Lymphocyte cytosolic protein 2a.	Uncharacterized protein.	0.586
ENSTRUP00000053105	ENSTRUP00000072102	ENSTRUP00000053105	ENSTRUP00000072102	Lymphocyte cytosolic protein 2a.	annotation not available	0.586
ENSTRUP00000053105	LOC101065481	ENSTRUP00000053105	ENSTRUP00000077824	Lymphocyte cytosolic protein 2a.	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1-like.	0.837
ENSTRUP00000053105	cd247	ENSTRUP00000053105	ENSTRUP00000072830	Lymphocyte cytosolic protein 2a.	Uncharacterized protein.	0.807
ENSTRUP00000053105	cd3e	ENSTRUP00000053105	ENSTRUP00000059068	Lymphocyte cytosolic protein 2a.	Ig_4 domain-containing protein.	0.727
ENSTRUP00000053105	cd3g/d	ENSTRUP00000053105	ENSTRUP00000008910	Lymphocyte cytosolic protein 2a.	Ig_4 domain-containing protein.	0.789
ENSTRUP00000053105	plcg1	ENSTRUP00000053105	ENSTRUP00000058192	Lymphocyte cytosolic protein 2a.	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades.	0.837
ENSTRUP00000053105	plcg2	ENSTRUP00000053105	ENSTRUP00000017918	Lymphocyte cytosolic protein 2a.	Phosphoinositide phospholipase C.	0.837
ENSTRUP00000053105	tyrobp	ENSTRUP00000053105	ENSTRUP00000055058	Lymphocyte cytosolic protein 2a.	Uncharacterized protein.	0.773
ENSTRUP00000053105	zap70	ENSTRUP00000053105	ENSTRUP00000073768	Lymphocyte cytosolic protein 2a.	Tyrosine-protein kinase.	0.814
ENSTRUP00000053545	ENSTRUP00000053105	ENSTRUP00000053545	ENSTRUP00000053105	Uncharacterized protein.	Lymphocyte cytosolic protein 2a.	0.586
ENSTRUP00000053545	LOC101065481	ENSTRUP00000053545	ENSTRUP00000077824	Uncharacterized protein.	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1-like.	0.429
ENSTRUP00000053545	cd247	ENSTRUP00000053545	ENSTRUP00000072830	Uncharacterized protein.	Uncharacterized protein.	0.449
ENSTRUP00000053545	plcg1	ENSTRUP00000053545	ENSTRUP00000058192	Uncharacterized protein.	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades.	0.429
ENSTRUP00000053545	plcg2	ENSTRUP00000053545	ENSTRUP00000017918	Uncharacterized protein.	Phosphoinositide phospholipase C.	0.429
ENSTRUP00000053545	tyrobp	ENSTRUP00000053545	ENSTRUP00000055058	Uncharacterized protein.	Uncharacterized protein.	0.931
ENSTRUP00000053545	zap70	ENSTRUP00000053545	ENSTRUP00000073768	Uncharacterized protein.	Tyrosine-protein kinase.	0.775
ENSTRUP00000072102	ENSTRUP00000053105	ENSTRUP00000072102	ENSTRUP00000053105	annotation not available	Lymphocyte cytosolic protein 2a.	0.586
ENSTRUP00000072102	LOC101065481	ENSTRUP00000072102	ENSTRUP00000077824	annotation not available	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1-like.	0.429
ENSTRUP00000072102	cd247	ENSTRUP00000072102	ENSTRUP00000072830	annotation not available	Uncharacterized protein.	0.449