ing1 protein (Takifugu rubripes) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

ing1

Inhibitor of growth protein. (320 aa)

Predicted Functional Partners:

suds3

0.881

meaf6

0.800

LOC101074167

0.761

rbbp4

0.761

LOC101079595

0.746

trrap

0.720

dmap1

0.699

sap30l

0.687

sin3a

0.684

sinhcaf

0.684

Your Current Organism:

Takifugu rubripes

NCBI taxonomy Id: 31033
Other names: Fugu rubripes, Sphaeroides rubripes, T. rubripes, Tetraodon rubripes, tiger puffer, torafugu

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
LOC101074167	LOC101079595	ENSTRUP00000001421	ENSTRUP00000030644	WD_REPEATS_REGION domain-containing protein.	Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family.	0.411
LOC101074167	ing1	ENSTRUP00000001421	ENSTRUP00000076281	WD_REPEATS_REGION domain-containing protein.	Inhibitor of growth protein.	0.761
LOC101074167	rbbp4	ENSTRUP00000001421	ENSTRUP00000048021	WD_REPEATS_REGION domain-containing protein.	Retinoblastoma binding protein 4.	0.900
LOC101074167	sap30l	ENSTRUP00000001421	ENSTRUP00000062978	WD_REPEATS_REGION domain-containing protein.	Sap30-like.	0.854
LOC101074167	sin3a	ENSTRUP00000001421	ENSTRUP00000040896	WD_REPEATS_REGION domain-containing protein.	SIN3 transcription regulator family member Aa.	0.775
LOC101074167	sinhcaf	ENSTRUP00000001421	ENSTRUP00000051376	WD_REPEATS_REGION domain-containing protein.	SIN3-HDAC complex associated factor.	0.490
LOC101074167	suds3	ENSTRUP00000001421	ENSTRUP00000054251	WD_REPEATS_REGION domain-containing protein.	SDS3 homolog, SIN3A corepressor complex component.	0.916
LOC101079595	LOC101074167	ENSTRUP00000030644	ENSTRUP00000001421	Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family.	WD_REPEATS_REGION domain-containing protein.	0.411
LOC101079595	ing1	ENSTRUP00000030644	ENSTRUP00000076281	Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family.	Inhibitor of growth protein.	0.746
LOC101079595	meaf6	ENSTRUP00000030644	ENSTRUP00000025573	Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family.	MYST/Esa1-associated factor 6.	0.503
LOC101079595	rbbp4	ENSTRUP00000030644	ENSTRUP00000048021	Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family.	Retinoblastoma binding protein 4.	0.411
LOC101079595	sin3a	ENSTRUP00000030644	ENSTRUP00000040896	Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family.	SIN3 transcription regulator family member Aa.	0.424
LOC101079595	trrap	ENSTRUP00000030644	ENSTRUP00000065709	Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family.	Transformation/transcription domain-associated protein; Belongs to the PI3/PI4-kinase family.	0.644
dmap1	ing1	ENSTRUP00000081832	ENSTRUP00000076281	DNA methyltransferase 1 associated protein 1.	Inhibitor of growth protein.	0.699
dmap1	meaf6	ENSTRUP00000081832	ENSTRUP00000025573	DNA methyltransferase 1 associated protein 1.	MYST/Esa1-associated factor 6.	0.987
dmap1	trrap	ENSTRUP00000081832	ENSTRUP00000065709	DNA methyltransferase 1 associated protein 1.	Transformation/transcription domain-associated protein; Belongs to the PI3/PI4-kinase family.	0.989
ing1	LOC101074167	ENSTRUP00000076281	ENSTRUP00000001421	Inhibitor of growth protein.	WD_REPEATS_REGION domain-containing protein.	0.761
ing1	LOC101079595	ENSTRUP00000076281	ENSTRUP00000030644	Inhibitor of growth protein.	Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family.	0.746
ing1	dmap1	ENSTRUP00000076281	ENSTRUP00000081832	Inhibitor of growth protein.	DNA methyltransferase 1 associated protein 1.	0.699
ing1	meaf6	ENSTRUP00000076281	ENSTRUP00000025573	Inhibitor of growth protein.	MYST/Esa1-associated factor 6.	0.800