| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| NUBP1 | abcb7 | ENSTRUP00000076875 | ENSTRUP00000075753 | Cytosolic Fe-S cluster assembly factor NUBP1; Component of the cytosolic iron-sulfur (Fe/S) protein assembly (CIA) machinery. Required for maturation of extramitochondrial Fe-S proteins. The NUBP1-NUBP2 heterotetramer forms a Fe-S scaffold complex, mediating the de novo assembly of an Fe-S cluster and its transfer to target apoproteins; Belongs to the Mrp/NBP35 ATP-binding proteins family. NUBP1/NBP35 subfamily. | ATP-binding cassette, sub-family B (MDR/TAP), member 7. | 0.807 |
| NUBP1 | asmtl | ENSTRUP00000076875 | ENSTRUP00000032521 | Cytosolic Fe-S cluster assembly factor NUBP1; Component of the cytosolic iron-sulfur (Fe/S) protein assembly (CIA) machinery. Required for maturation of extramitochondrial Fe-S proteins. The NUBP1-NUBP2 heterotetramer forms a Fe-S scaffold complex, mediating the de novo assembly of an Fe-S cluster and its transfer to target apoproteins; Belongs to the Mrp/NBP35 ATP-binding proteins family. NUBP1/NBP35 subfamily. | Acetylserotonin O-methyltransferase-like. | 0.788 |
| NUBP1 | ciao3 | ENSTRUP00000076875 | ENSTRUP00000013401 | Cytosolic Fe-S cluster assembly factor NUBP1; Component of the cytosolic iron-sulfur (Fe/S) protein assembly (CIA) machinery. Required for maturation of extramitochondrial Fe-S proteins. The NUBP1-NUBP2 heterotetramer forms a Fe-S scaffold complex, mediating the de novo assembly of an Fe-S cluster and its transfer to target apoproteins; Belongs to the Mrp/NBP35 ATP-binding proteins family. NUBP1/NBP35 subfamily. | Nuclear prelamin A recognition factor-like; Belongs to the NARF family. | 0.847 |
| NUBP1 | ciapin1 | ENSTRUP00000076875 | ENSTRUP00000072796 | Cytosolic Fe-S cluster assembly factor NUBP1; Component of the cytosolic iron-sulfur (Fe/S) protein assembly (CIA) machinery. Required for maturation of extramitochondrial Fe-S proteins. The NUBP1-NUBP2 heterotetramer forms a Fe-S scaffold complex, mediating the de novo assembly of an Fe-S cluster and its transfer to target apoproteins; Belongs to the Mrp/NBP35 ATP-binding proteins family. NUBP1/NBP35 subfamily. | Anamorsin; Component of the cytosolic iron-sulfur (Fe-S) protein assembly (CIA) machinery required for the maturation of extramitochondrial Fe-S proteins. Part of an electron transfer chain functioning in an early step of cytosolic Fe-S biogenesis, facilitating the de novo assembly of a [4Fe-4S] cluster on the scaffold complex NUBP1-NUBP2. Electrons are transferred to CIAPIN1 from NADPH via the FAD- and FMN-containing protein NDOR1. NDOR1-CIAPIN1 are also required for the assembly of the diferric tyrosyl radical cofactor of ribonucleotide reductase (RNR), probably by providing electron [...] | 0.881 |
| NUBP1 | fpgs | ENSTRUP00000076875 | ENSTRUP00000068068 | Cytosolic Fe-S cluster assembly factor NUBP1; Component of the cytosolic iron-sulfur (Fe/S) protein assembly (CIA) machinery. Required for maturation of extramitochondrial Fe-S proteins. The NUBP1-NUBP2 heterotetramer forms a Fe-S scaffold complex, mediating the de novo assembly of an Fe-S cluster and its transfer to target apoproteins; Belongs to the Mrp/NBP35 ATP-binding proteins family. NUBP1/NBP35 subfamily. | Folylpolyglutamate synthase; Catalyzes conversion of folates to polyglutamate derivatives allowing concentration of folate compounds in the cell and the intracellular retention of these cofactors, which are important substrates for most of the folate-dependent enzymes that are involved in one-carbon transfer reactions involved in purine, pyrimidine and amino acid synthesis; Belongs to the folylpolyglutamate synthase family. | 0.746 |
| NUBP1 | mms19 | ENSTRUP00000076875 | ENSTRUP00000043827 | Cytosolic Fe-S cluster assembly factor NUBP1; Component of the cytosolic iron-sulfur (Fe/S) protein assembly (CIA) machinery. Required for maturation of extramitochondrial Fe-S proteins. The NUBP1-NUBP2 heterotetramer forms a Fe-S scaffold complex, mediating the de novo assembly of an Fe-S cluster and its transfer to target apoproteins; Belongs to the Mrp/NBP35 ATP-binding proteins family. NUBP1/NBP35 subfamily. | MMS19 homolog, cytosolic iron-sulfur assembly component. | 0.733 |
| NUBP1 | narf | ENSTRUP00000076875 | ENSTRUP00000076381 | Cytosolic Fe-S cluster assembly factor NUBP1; Component of the cytosolic iron-sulfur (Fe/S) protein assembly (CIA) machinery. Required for maturation of extramitochondrial Fe-S proteins. The NUBP1-NUBP2 heterotetramer forms a Fe-S scaffold complex, mediating the de novo assembly of an Fe-S cluster and its transfer to target apoproteins; Belongs to the Mrp/NBP35 ATP-binding proteins family. NUBP1/NBP35 subfamily. | Nuclear prelamin A recognition factor; Belongs to the NARF family. | 0.847 |
| NUBP1 | ndufs2 | ENSTRUP00000076875 | ENSTRUP00000030130 | Cytosolic Fe-S cluster assembly factor NUBP1; Component of the cytosolic iron-sulfur (Fe/S) protein assembly (CIA) machinery. Required for maturation of extramitochondrial Fe-S proteins. The NUBP1-NUBP2 heterotetramer forms a Fe-S scaffold complex, mediating the de novo assembly of an Fe-S cluster and its transfer to target apoproteins; Belongs to the Mrp/NBP35 ATP-binding proteins family. NUBP1/NBP35 subfamily. | NADH:ubiquinone oxidoreductase core subunit S2; Belongs to the complex I 49 kDa subunit family. | 0.756 |
| NUBP1 | ndufs3 | ENSTRUP00000076875 | ENSTRUP00000061860 | Cytosolic Fe-S cluster assembly factor NUBP1; Component of the cytosolic iron-sulfur (Fe/S) protein assembly (CIA) machinery. Required for maturation of extramitochondrial Fe-S proteins. The NUBP1-NUBP2 heterotetramer forms a Fe-S scaffold complex, mediating the de novo assembly of an Fe-S cluster and its transfer to target apoproteins; Belongs to the Mrp/NBP35 ATP-binding proteins family. NUBP1/NBP35 subfamily. | NADH:ubiquinone oxidoreductase core subunit S3; Belongs to the complex I 30 kDa subunit family. | 0.714 |
| NUBP1 | nfs1 | ENSTRUP00000076875 | ENSTRUP00000059662 | Cytosolic Fe-S cluster assembly factor NUBP1; Component of the cytosolic iron-sulfur (Fe/S) protein assembly (CIA) machinery. Required for maturation of extramitochondrial Fe-S proteins. The NUBP1-NUBP2 heterotetramer forms a Fe-S scaffold complex, mediating the de novo assembly of an Fe-S cluster and its transfer to target apoproteins; Belongs to the Mrp/NBP35 ATP-binding proteins family. NUBP1/NBP35 subfamily. | NFS1 cysteine desulfurase. | 0.736 |
| abcb7 | NUBP1 | ENSTRUP00000075753 | ENSTRUP00000076875 | ATP-binding cassette, sub-family B (MDR/TAP), member 7. | Cytosolic Fe-S cluster assembly factor NUBP1; Component of the cytosolic iron-sulfur (Fe/S) protein assembly (CIA) machinery. Required for maturation of extramitochondrial Fe-S proteins. The NUBP1-NUBP2 heterotetramer forms a Fe-S scaffold complex, mediating the de novo assembly of an Fe-S cluster and its transfer to target apoproteins; Belongs to the Mrp/NBP35 ATP-binding proteins family. NUBP1/NBP35 subfamily. | 0.807 |
| abcb7 | ciao3 | ENSTRUP00000075753 | ENSTRUP00000013401 | ATP-binding cassette, sub-family B (MDR/TAP), member 7. | Nuclear prelamin A recognition factor-like; Belongs to the NARF family. | 0.475 |
| abcb7 | ciapin1 | ENSTRUP00000075753 | ENSTRUP00000072796 | ATP-binding cassette, sub-family B (MDR/TAP), member 7. | Anamorsin; Component of the cytosolic iron-sulfur (Fe-S) protein assembly (CIA) machinery required for the maturation of extramitochondrial Fe-S proteins. Part of an electron transfer chain functioning in an early step of cytosolic Fe-S biogenesis, facilitating the de novo assembly of a [4Fe-4S] cluster on the scaffold complex NUBP1-NUBP2. Electrons are transferred to CIAPIN1 from NADPH via the FAD- and FMN-containing protein NDOR1. NDOR1-CIAPIN1 are also required for the assembly of the diferric tyrosyl radical cofactor of ribonucleotide reductase (RNR), probably by providing electron [...] | 0.599 |
| abcb7 | mms19 | ENSTRUP00000075753 | ENSTRUP00000043827 | ATP-binding cassette, sub-family B (MDR/TAP), member 7. | MMS19 homolog, cytosolic iron-sulfur assembly component. | 0.572 |
| abcb7 | narf | ENSTRUP00000075753 | ENSTRUP00000076381 | ATP-binding cassette, sub-family B (MDR/TAP), member 7. | Nuclear prelamin A recognition factor; Belongs to the NARF family. | 0.475 |
| abcb7 | nfs1 | ENSTRUP00000075753 | ENSTRUP00000059662 | ATP-binding cassette, sub-family B (MDR/TAP), member 7. | NFS1 cysteine desulfurase. | 0.683 |
| asmtl | NUBP1 | ENSTRUP00000032521 | ENSTRUP00000076875 | Acetylserotonin O-methyltransferase-like. | Cytosolic Fe-S cluster assembly factor NUBP1; Component of the cytosolic iron-sulfur (Fe/S) protein assembly (CIA) machinery. Required for maturation of extramitochondrial Fe-S proteins. The NUBP1-NUBP2 heterotetramer forms a Fe-S scaffold complex, mediating the de novo assembly of an Fe-S cluster and its transfer to target apoproteins; Belongs to the Mrp/NBP35 ATP-binding proteins family. NUBP1/NBP35 subfamily. | 0.788 |
| asmtl | fpgs | ENSTRUP00000032521 | ENSTRUP00000068068 | Acetylserotonin O-methyltransferase-like. | Folylpolyglutamate synthase; Catalyzes conversion of folates to polyglutamate derivatives allowing concentration of folate compounds in the cell and the intracellular retention of these cofactors, which are important substrates for most of the folate-dependent enzymes that are involved in one-carbon transfer reactions involved in purine, pyrimidine and amino acid synthesis; Belongs to the folylpolyglutamate synthase family. | 0.565 |
| ciao3 | NUBP1 | ENSTRUP00000013401 | ENSTRUP00000076875 | Nuclear prelamin A recognition factor-like; Belongs to the NARF family. | Cytosolic Fe-S cluster assembly factor NUBP1; Component of the cytosolic iron-sulfur (Fe/S) protein assembly (CIA) machinery. Required for maturation of extramitochondrial Fe-S proteins. The NUBP1-NUBP2 heterotetramer forms a Fe-S scaffold complex, mediating the de novo assembly of an Fe-S cluster and its transfer to target apoproteins; Belongs to the Mrp/NBP35 ATP-binding proteins family. NUBP1/NBP35 subfamily. | 0.847 |
| ciao3 | abcb7 | ENSTRUP00000013401 | ENSTRUP00000075753 | Nuclear prelamin A recognition factor-like; Belongs to the NARF family. | ATP-binding cassette, sub-family B (MDR/TAP), member 7. | 0.475 |
