node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
hemk1 | n6amt1 | ENSTRUP00000073650 | ENSTRUP00000034704 | HemK methyltransferase family member 1. | N-6 adenine-specific DNA methyltransferase 1. | 0.654 |
hemk1 | osgep | ENSTRUP00000073650 | ENSTRUP00000072956 | HemK methyltransferase family member 1. | Probable tRNA N6-adenosine threonylcarbamoyltransferase; Component of the EKC/KEOPS complex that is required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. The complex is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. OSGEP likely plays a direct catalytic role in this reaction, but requires other protein(s) of the complex to fulfill this activity. | 0.400 |
hemk1 | osgepl1 | ENSTRUP00000073650 | ENSTRUP00000032107 | HemK methyltransferase family member 1. | Probable tRNA N6-adenosine threonylcarbamoyltransferase, mitochondrial; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in mitochondrial tRNAs that read codons beginning with adenine. Probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. Involved in mitochondrial genome maintenance. | 0.400 |
hemk1 | wdr4 | ENSTRUP00000073650 | ENSTRUP00000005136 | HemK methyltransferase family member 1. | tRNA (guanine-N(7)-)-methyltransferase non-catalytic subunit WDR4; Required for the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA. In the complex, it is required to stabilize and induce conformational changes of the catalytic subunit. Belongs to the WD repeat TRM82 family. | 0.403 |
hemk1 | yrdc | ENSTRUP00000073650 | ENSTRUP00000078813 | HemK methyltransferase family member 1. | YrdC N(6)-threonylcarbamoyltransferase domain containing. | 0.505 |
mettl1 | n6amt1 | ENSTRUP00000047402 | ENSTRUP00000034704 | tRNA (guanine-N(7)-)-methyltransferase; Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA. | N-6 adenine-specific DNA methyltransferase 1. | 0.460 |
mettl1 | wdr4 | ENSTRUP00000047402 | ENSTRUP00000005136 | tRNA (guanine-N(7)-)-methyltransferase; Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA. | tRNA (guanine-N(7)-)-methyltransferase non-catalytic subunit WDR4; Required for the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA. In the complex, it is required to stabilize and induce conformational changes of the catalytic subunit. Belongs to the WD repeat TRM82 family. | 0.999 |
mettl1 | yrdc | ENSTRUP00000047402 | ENSTRUP00000078813 | tRNA (guanine-N(7)-)-methyltransferase; Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA. | YrdC N(6)-threonylcarbamoyltransferase domain containing. | 0.652 |
n6amt1 | hemk1 | ENSTRUP00000034704 | ENSTRUP00000073650 | N-6 adenine-specific DNA methyltransferase 1. | HemK methyltransferase family member 1. | 0.654 |
n6amt1 | mettl1 | ENSTRUP00000034704 | ENSTRUP00000047402 | N-6 adenine-specific DNA methyltransferase 1. | tRNA (guanine-N(7)-)-methyltransferase; Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA. | 0.460 |
n6amt1 | osgep | ENSTRUP00000034704 | ENSTRUP00000072956 | N-6 adenine-specific DNA methyltransferase 1. | Probable tRNA N6-adenosine threonylcarbamoyltransferase; Component of the EKC/KEOPS complex that is required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. The complex is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. OSGEP likely plays a direct catalytic role in this reaction, but requires other protein(s) of the complex to fulfill this activity. | 0.400 |
n6amt1 | osgepl1 | ENSTRUP00000034704 | ENSTRUP00000032107 | N-6 adenine-specific DNA methyltransferase 1. | Probable tRNA N6-adenosine threonylcarbamoyltransferase, mitochondrial; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in mitochondrial tRNAs that read codons beginning with adenine. Probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. Involved in mitochondrial genome maintenance. | 0.400 |
n6amt1 | wdr4 | ENSTRUP00000034704 | ENSTRUP00000005136 | N-6 adenine-specific DNA methyltransferase 1. | tRNA (guanine-N(7)-)-methyltransferase non-catalytic subunit WDR4; Required for the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA. In the complex, it is required to stabilize and induce conformational changes of the catalytic subunit. Belongs to the WD repeat TRM82 family. | 0.566 |
n6amt1 | yrdc | ENSTRUP00000034704 | ENSTRUP00000078813 | N-6 adenine-specific DNA methyltransferase 1. | YrdC N(6)-threonylcarbamoyltransferase domain containing. | 0.505 |
osgep | hemk1 | ENSTRUP00000072956 | ENSTRUP00000073650 | Probable tRNA N6-adenosine threonylcarbamoyltransferase; Component of the EKC/KEOPS complex that is required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. The complex is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. OSGEP likely plays a direct catalytic role in this reaction, but requires other protein(s) of the complex to fulfill this activity. | HemK methyltransferase family member 1. | 0.400 |
osgep | n6amt1 | ENSTRUP00000072956 | ENSTRUP00000034704 | Probable tRNA N6-adenosine threonylcarbamoyltransferase; Component of the EKC/KEOPS complex that is required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. The complex is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. OSGEP likely plays a direct catalytic role in this reaction, but requires other protein(s) of the complex to fulfill this activity. | N-6 adenine-specific DNA methyltransferase 1. | 0.400 |
osgep | osgepl1 | ENSTRUP00000072956 | ENSTRUP00000032107 | Probable tRNA N6-adenosine threonylcarbamoyltransferase; Component of the EKC/KEOPS complex that is required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. The complex is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. OSGEP likely plays a direct catalytic role in this reaction, but requires other protein(s) of the complex to fulfill this activity. | Probable tRNA N6-adenosine threonylcarbamoyltransferase, mitochondrial; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in mitochondrial tRNAs that read codons beginning with adenine. Probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. Involved in mitochondrial genome maintenance. | 0.586 |
osgep | pudp | ENSTRUP00000072956 | ENSTRUP00000007855 | Probable tRNA N6-adenosine threonylcarbamoyltransferase; Component of the EKC/KEOPS complex that is required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. The complex is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. OSGEP likely plays a direct catalytic role in this reaction, but requires other protein(s) of the complex to fulfill this activity. | Pseudouridine 5'-phosphatase. | 0.563 |
osgep | tp53rk | ENSTRUP00000072956 | ENSTRUP00000073227 | Probable tRNA N6-adenosine threonylcarbamoyltransferase; Component of the EKC/KEOPS complex that is required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. The complex is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. OSGEP likely plays a direct catalytic role in this reaction, but requires other protein(s) of the complex to fulfill this activity. | TP53 regulating kinase. | 0.995 |
osgep | yrdc | ENSTRUP00000072956 | ENSTRUP00000078813 | Probable tRNA N6-adenosine threonylcarbamoyltransferase; Component of the EKC/KEOPS complex that is required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. The complex is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. OSGEP likely plays a direct catalytic role in this reaction, but requires other protein(s) of the complex to fulfill this activity. | YrdC N(6)-threonylcarbamoyltransferase domain containing. | 0.772 |