node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ENSTRUP00000079261 | EZH1 | ENSTRUP00000079261 | ENSTRUP00000038365 | annotation not available | Enhancer of zeste 1 polycomb repressive complex 2 subunit. | 0.405 |
ENSTRUP00000079261 | LOC101079595 | ENSTRUP00000079261 | ENSTRUP00000030644 | annotation not available | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. | 0.425 |
ENSTRUP00000079261 | fbxw11 | ENSTRUP00000079261 | ENSTRUP00000068686 | annotation not available | F-box and WD repeat domain containing 11b. | 0.461 |
ENSTRUP00000079261 | kdm1a | ENSTRUP00000079261 | ENSTRUP00000031259 | annotation not available | Lysine-specific histone demethylase; Histone demethylase that demethylates both 'Lys-4' (H3K4me) and 'Lys-9' (H3K9me) of histone H3, thereby acting as a coactivator or a corepressor, depending on the context. Acts by oxidizing the substrate by FAD to generate the corresponding imine that is subsequently hydrolyzed. Acts as a corepressor by mediating demethylation of H3K4me, a specific tag for epigenetic transcriptional activation. Demethylates both mono- (H3K4me1) and di-methylated (H3K4me2) H3K4me; Belongs to the flavin monoamine oxidase family. | 0.646 |
ENSTRUP00000079261 | kpnb1 | ENSTRUP00000079261 | ENSTRUP00000001283 | annotation not available | Karyopherin (importin) beta 1. | 0.501 |
ENSTRUP00000079261 | rcor2 | ENSTRUP00000079261 | ENSTRUP00000070951 | annotation not available | REST corepressor 2. | 0.427 |
ENSTRUP00000079261 | rcor3 | ENSTRUP00000079261 | ENSTRUP00000035362 | annotation not available | REST corepressor 3. | 0.427 |
EZH1 | ENSTRUP00000079261 | ENSTRUP00000038365 | ENSTRUP00000079261 | Enhancer of zeste 1 polycomb repressive complex 2 subunit. | annotation not available | 0.405 |
EZH1 | LOC101079595 | ENSTRUP00000038365 | ENSTRUP00000030644 | Enhancer of zeste 1 polycomb repressive complex 2 subunit. | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. | 0.569 |
EZH1 | kdm1a | ENSTRUP00000038365 | ENSTRUP00000031259 | Enhancer of zeste 1 polycomb repressive complex 2 subunit. | Lysine-specific histone demethylase; Histone demethylase that demethylates both 'Lys-4' (H3K4me) and 'Lys-9' (H3K9me) of histone H3, thereby acting as a coactivator or a corepressor, depending on the context. Acts by oxidizing the substrate by FAD to generate the corresponding imine that is subsequently hydrolyzed. Acts as a corepressor by mediating demethylation of H3K4me, a specific tag for epigenetic transcriptional activation. Demethylates both mono- (H3K4me1) and di-methylated (H3K4me2) H3K4me; Belongs to the flavin monoamine oxidase family. | 0.637 |
LOC101079595 | ENSTRUP00000079261 | ENSTRUP00000030644 | ENSTRUP00000079261 | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. | annotation not available | 0.425 |
LOC101079595 | EZH1 | ENSTRUP00000030644 | ENSTRUP00000038365 | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. | Enhancer of zeste 1 polycomb repressive complex 2 subunit. | 0.569 |
LOC101079595 | kdm1a | ENSTRUP00000030644 | ENSTRUP00000031259 | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. | Lysine-specific histone demethylase; Histone demethylase that demethylates both 'Lys-4' (H3K4me) and 'Lys-9' (H3K9me) of histone H3, thereby acting as a coactivator or a corepressor, depending on the context. Acts by oxidizing the substrate by FAD to generate the corresponding imine that is subsequently hydrolyzed. Acts as a corepressor by mediating demethylation of H3K4me, a specific tag for epigenetic transcriptional activation. Demethylates both mono- (H3K4me1) and di-methylated (H3K4me2) H3K4me; Belongs to the flavin monoamine oxidase family. | 0.673 |
fbxw11 | ENSTRUP00000079261 | ENSTRUP00000068686 | ENSTRUP00000079261 | F-box and WD repeat domain containing 11b. | annotation not available | 0.461 |
kdm1a | ENSTRUP00000079261 | ENSTRUP00000031259 | ENSTRUP00000079261 | Lysine-specific histone demethylase; Histone demethylase that demethylates both 'Lys-4' (H3K4me) and 'Lys-9' (H3K9me) of histone H3, thereby acting as a coactivator or a corepressor, depending on the context. Acts by oxidizing the substrate by FAD to generate the corresponding imine that is subsequently hydrolyzed. Acts as a corepressor by mediating demethylation of H3K4me, a specific tag for epigenetic transcriptional activation. Demethylates both mono- (H3K4me1) and di-methylated (H3K4me2) H3K4me; Belongs to the flavin monoamine oxidase family. | annotation not available | 0.646 |
kdm1a | EZH1 | ENSTRUP00000031259 | ENSTRUP00000038365 | Lysine-specific histone demethylase; Histone demethylase that demethylates both 'Lys-4' (H3K4me) and 'Lys-9' (H3K9me) of histone H3, thereby acting as a coactivator or a corepressor, depending on the context. Acts by oxidizing the substrate by FAD to generate the corresponding imine that is subsequently hydrolyzed. Acts as a corepressor by mediating demethylation of H3K4me, a specific tag for epigenetic transcriptional activation. Demethylates both mono- (H3K4me1) and di-methylated (H3K4me2) H3K4me; Belongs to the flavin monoamine oxidase family. | Enhancer of zeste 1 polycomb repressive complex 2 subunit. | 0.637 |
kdm1a | LOC101079595 | ENSTRUP00000031259 | ENSTRUP00000030644 | Lysine-specific histone demethylase; Histone demethylase that demethylates both 'Lys-4' (H3K4me) and 'Lys-9' (H3K9me) of histone H3, thereby acting as a coactivator or a corepressor, depending on the context. Acts by oxidizing the substrate by FAD to generate the corresponding imine that is subsequently hydrolyzed. Acts as a corepressor by mediating demethylation of H3K4me, a specific tag for epigenetic transcriptional activation. Demethylates both mono- (H3K4me1) and di-methylated (H3K4me2) H3K4me; Belongs to the flavin monoamine oxidase family. | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. | 0.673 |
kdm1a | rcor2 | ENSTRUP00000031259 | ENSTRUP00000070951 | Lysine-specific histone demethylase; Histone demethylase that demethylates both 'Lys-4' (H3K4me) and 'Lys-9' (H3K9me) of histone H3, thereby acting as a coactivator or a corepressor, depending on the context. Acts by oxidizing the substrate by FAD to generate the corresponding imine that is subsequently hydrolyzed. Acts as a corepressor by mediating demethylation of H3K4me, a specific tag for epigenetic transcriptional activation. Demethylates both mono- (H3K4me1) and di-methylated (H3K4me2) H3K4me; Belongs to the flavin monoamine oxidase family. | REST corepressor 2. | 0.970 |
kdm1a | rcor3 | ENSTRUP00000031259 | ENSTRUP00000035362 | Lysine-specific histone demethylase; Histone demethylase that demethylates both 'Lys-4' (H3K4me) and 'Lys-9' (H3K9me) of histone H3, thereby acting as a coactivator or a corepressor, depending on the context. Acts by oxidizing the substrate by FAD to generate the corresponding imine that is subsequently hydrolyzed. Acts as a corepressor by mediating demethylation of H3K4me, a specific tag for epigenetic transcriptional activation. Demethylates both mono- (H3K4me1) and di-methylated (H3K4me2) H3K4me; Belongs to the flavin monoamine oxidase family. | REST corepressor 3. | 0.970 |
kpnb1 | ENSTRUP00000079261 | ENSTRUP00000001283 | ENSTRUP00000079261 | Karyopherin (importin) beta 1. | annotation not available | 0.501 |