STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
erbb4Receptor protein-tyrosine kinase. (1406 aa)    
Predicted Functional Partners:
grb2
Growth factor receptor-bound protein 2b.
    
 0.974
LOC101061204
Uncharacterized protein.
    
 0.974
SHC3
SHC adaptor protein 3.
    
 0.969
shc1
SHC (Src homology 2 domain containing) transforming protein 1.
    
 0.969
nrg2
Neuregulin 2a.
    
 0.969
LOC101075752
Neuregulin 2b.
    
 0.969
shc4
SHC-transforming protein 4 isoform X2.
    
 0.969
hbegf
Heparin-binding EGF-like growth factor a.
    
 0.964
shc2
SHC (Src homology 2 domain containing) transforming protein 2.
    
 0.962
LOC101071345
Signal transducer and activator of transcription.
    
 0.950
Your Current Organism:
Takifugu rubripes
NCBI taxonomy Id: 31033
Other names: Fugu rubripes, Sphaeroides rubripes, T. rubripes, Tetraodon rubripes, tiger puffer, torafugu
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.