STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ube2aUbiquitin-conjugating enzyme E2A (RAD6 homolog); Belongs to the ubiquitin-conjugating enzyme family. (152 aa)    
Predicted Functional Partners:
leo1
LEO1 homolog, Paf1/RNA polymerase II complex component.
   
 0.951
rps27a
Ribosomal protein S27a.
   
 0.920
RAD18
RAD18 E3 ubiquitin protein ligase.
    
 0.915
ENSTRUP00000088043
E3 ubiquitin-protein ligase RAD18 isoform X1.
    
 0.915
rnf20
E3 ubiquitin protein ligase.
   
 0.895
rnf40
E3 ubiquitin protein ligase.
   
 0.895
ube2v2
Ubiquitin-conjugating enzyme E2 variant 2.
   
 0.894
trip12
Thyroid hormone receptor interactor 12.
   
 0.880
pcna
Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.
   
 0.868
LOC101071293
Ubiquitin-like modifier activating enzyme 7; Belongs to the ubiquitin-activating E1 family.
   
 0.843
Your Current Organism:
Takifugu rubripes
NCBI taxonomy Id: 31033
Other names: Fugu rubripes, Sphaeroides rubripes, T. rubripes, Tetraodon rubripes, tiger puffer, torafugu
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.