close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
GPR161G-protein coupled receptor 161; Belongs to the G-protein coupled receptor 1 family. (528 aa)    
Predicted Functional Partners:
ARRB1
Beta-arrestin-1 isoform X1.
   
 0.933
EVC2
LOW QUALITY PROTEIN: limbin.
      
 0.775
SMO
Smoothened homolog; Belongs to the G-protein coupled receptor Fz/Smo family.
     
 0.759
ARL13B
ADP-ribosylation factor-like protein 13B isoform X1.
      
 0.756
SUFU
Suppressor of fused homolog; Negative regulator in the hedgehog signaling pathway. Down- regulates GLI1-mediated transactivation of target genes. Part of a corepressor complex that acts on DNA-bound GLI1. May also act by linking GLI1 to BTRC and thereby targeting GLI1 to degradation by the proteasome. Sequesters GLI1, GLI2 and GLI3 in the cytoplasm, this effect is overcome by binding of STK36 to both SUFU and a GLI protein. Negative regulator of beta-catenin signaling. Regulates the formation of either the repressor form (GLI3R) or the activator form (GLI3A) of the full-length form of [...]
      
 0.721
IFT122
Intraflagellar transport protein 122 homolog isoform X3.
     
 0.703
TULP1
Tubby-like protein; Belongs to the TUB family.
     
 0.692
TULP3
Tubby-like protein; Belongs to the TUB family.
     
 0.691
LOC103016245
LOW QUALITY PROTEIN: tubby-related protein 3-like; Belongs to the TUB family.
     
 0.691
DLG5
Disks large homolog 5; Belongs to the MAGUK family.
    
 
 0.685
Your Current Organism:
Balaenoptera acutorostrata
NCBI taxonomy Id: 310752
Other names: B. acutorostrata scammoni, Balaenoptera acutorostrata scammoni
Server load: low (22%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.