STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TNFRSF11BTumor necrosis factor receptor superfamily member 11B; Acts as decoy receptor for TNFSF11/RANKL and thereby neutralizes its function in osteoclastogenesis. (401 aa)    
Predicted Functional Partners:
TNFSF11
Tumor necrosis factor ligand superfamily member 11; Belongs to the tumor necrosis factor family.
   
 0.997
PIK3CB
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform; Belongs to the PI3/PI4-kinase family.
   
 
 0.813
NCF2
Neutrophil cytosol factor 2.
      
 0.807
TGFB2
Transforming growth factor beta; Belongs to the TGF-beta family.
   
  
 0.747
TNFSF18
Tumor necrosis factor ligand superfamily member 18.
   
 0.731
CTSK
Cathepsin K isoform X1; Belongs to the peptidase C1 family.
   
  
 0.729
MAPK13
Mitogen-activated protein kinase.
      
 0.728
LCK
Tyrosine-protein kinase.
    
 
 0.720
CD40LG
CD40 ligand; Cytokine that acts as a ligand to CD40/TNFRSF5. Costimulates T-cell proliferation and cytokine production. Involved in immunoglobulin class switching.
   
 0.656
GRB2
Growth factor receptor-bound protein 2.
   
 
 0.649
Your Current Organism:
Balaenoptera acutorostrata
NCBI taxonomy Id: 310752
Other names: B. acutorostrata scammoni, Balaenoptera acutorostrata scammoni
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