STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SEN36747.1Dihydrofolate reductase. (211 aa)    
Predicted Functional Partners:
SEO66902.1
Methionine synthase (B12-dependent); Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
    
 0.643
SEN15491.1
Dihydrofolate reductase.
 
     0.604
SEN36730.1
Maleylpyruvate isomerase.
 
     0.571
SEO88687.1
Dihydrofolate reductase.
  
     0.508
SEO29004.1
RibD C-terminal domain-containing protein.
  
     0.500
SEN80299.1
RibD C-terminal domain-containing protein.
  
     0.473
SEN97003.1
Dihydrofolate reductase.
  
     0.469
SEO86784.1
Dihydrofolate reductase.
  
     0.459
SEO63301.1
Transcriptional regulator, TetR family.
  
     0.456
SEP00436.1
Transcriptional regulator, TetR family.
  
     0.456
Your Current Organism:
Streptomyces rubidus
NCBI taxonomy Id: 310780
Other names: CGMCC 4.2026, JCM 13277, NBRC 102073, S. rubidus, Streptomyces rubidus Xu et al. 2006, Streptomyces sp. 13c15, strain 13c15
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