STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SEO33350.1TIGR02452 family protein. (286 aa)    
Predicted Functional Partners:
SEO33363.1
Ala-tRNA(Pro) deacylase.
       0.783
SEN38180.1
ADP-ribosylglycohydrolase.
 
   
 0.727
SEP06882.1
ADP-ribosylglycohydrolase.
 
   
 0.687
SEN83587.1
Hypothetical protein.
 
     0.679
SEN08244.1
O-acetyl-ADP-ribose deacetylase (regulator of RNase III), contains Macro domain.
     
 0.646
egtA
Glutamate--cysteine ligase; Catalyzes the synthesis of gamma-glutamylcysteine (gamma-GC). This compound is used as substrate for the biosynthesis of the low- molecular thiol compound ergothioneine.
       0.603
egtB
iron(II)-dependent oxidoreductase; Catalyzes the oxidative sulfurization of hercynine (N- alpha,N-alpha,N-alpha-trimethyl-L-histidine) into hercynyl-gamma-L- glutamyl-L-cysteine sulfoxide, a step in the biosynthesis pathway of ergothioneine; Belongs to the EgtB family.
       0.603
egtC
Dimethylhistidine N-methyltransferase; Catalyzes the hydrolysis of the gamma-glutamyl amide bond of hercynyl-gamma-L-glutamyl-L-cysteine sulfoxide to produce hercynylcysteine sulfoxide, a step in the biosynthesis pathway of ergothioneine.
       0.603
SEP08427.1
Predicted NAD-dependent protein-ADP-ribosyltransferase YbiA, DUF1768 family.
 
     0.582
SEO33328.1
Nucleoside-diphosphate-sugar epimerase.
       0.551
Your Current Organism:
Streptomyces rubidus
NCBI taxonomy Id: 310780
Other names: CGMCC 4.2026, JCM 13277, NBRC 102073, S. rubidus, Streptomyces rubidus Xu et al. 2006, Streptomyces sp. 13c15, strain 13c15
Server load: low (16%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.