STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
cobBCobyrinic acid a,c-diamide synthase; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of hydrogenobyrinate, using either L- glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family. (461 aa)    
Predicted Functional Partners:
SEO75824.1
precorrin-8X methylmutase.
 
 0.999
SEO75698.1
Cobaltochelatase CobN subunit.
 
 
 0.998
SEO75731.1
cob(I)yrinic acid a,c-diamide adenosyltransferase.
 
 
 0.997
SEO75806.1
Cobalt-precorrin 5A hydrolase / precorrin-3B C17-methyltransferase.
 
  
 0.997
cobQ
Adenosylcobyric acid synthase (glutamine-hydrolysing); Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation. Belongs to the CobB/CobQ family. CobQ subfamily.
  
 0.994
cobD
Adenosylcobinamide-phosphate synthase; Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group.
 
 0.987
SEO75777.1
Precorrin-4 C11-methyltransferase.
 
  
 0.987
SEO75759.1
Precorrin-2 C20-methyltransferase /cobalt-factor II C20-methyltransferase.
 
  
 0.979
SEO75712.1
Protoporphyrin IX magnesium-chelatase.
 
   
 0.978
SEO75792.1
precorrin-6Y C5,15-methyltransferase (decarboxylating).
 
  
 0.977
Your Current Organism:
Streptomyces rubidus
NCBI taxonomy Id: 310780
Other names: CGMCC 4.2026, JCM 13277, NBRC 102073, S. rubidus, Streptomyces rubidus Xu et al. 2006, Streptomyces sp. 13c15, strain 13c15
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