STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SDO18718.1Ribonucleoside-diphosphate reductase beta chain. (334 aa)    
Predicted Functional Partners:
SDN25266.1
Ribonucleoside-diphosphate reductase alpha chain; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.
  
 0.990
SDO74724.1
Ribonucleoside-diphosphate reductase class II; Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen.
  
 0.990
SDN48022.1
Phosphopantetheine attachment site.
  
 0.932
SDP35570.1
Acyl transferase domain-containing protein.
    
 0.885
SDN25298.1
Ribonucleoside-diphosphate reductase beta chain; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides; Belongs to the ribonucleoside diphosphate reductase small chain family.
     
 0.858
SDP33298.1
Amino acid adenylation domain-containing protein.
   
 0.856
SDO37327.1
Acyl transferase domain-containing protein.
    
 0.835
cmk
Cytidylate kinase.
    
 0.812
ndk
Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family.
     
 0.809
SDO18747.1
Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II.
 
     0.808
Your Current Organism:
Streptomyces guanduensis
NCBI taxonomy Id: 310781
Other names: CGMCC 4.2022, JCM 13274, NBRC 102070, S. guanduensis, Streptomyces guanduensis Xu et al. 2006, Streptomyces sp. 701, strain 701
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