STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SDO99334.1Acetyl esterase/lipase. (321 aa)    
Predicted Functional Partners:
SDP43080.1
NADH-quinone oxidoreductase subunit F.
    
  0.991
kynU
Kynureninase; Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively.
 
 
 0.974
kynA
Tryptophan 2,3-dioxygenase; Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L- tryptophan to N-formyl-L-kynurenine. Catalyzes the oxidative cleavage of the indole moiety.
 
 
 0.968
SDN48022.1
Phosphopantetheine attachment site.
  
 0.958
SDP33324.1
Phosphopantetheine attachment site.
  
 0.896
SDO37657.1
Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II.
 
 0.839
SDN48271.1
Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II.
 
 0.817
SDN47230.1
Natural product biosynthesis luciferase-like monooxygenase domain-containing protein.
  
 0.816
SDN90562.1
AMP-binding enzyme.
  
 0.808
SDO33694.1
NADH-quinone oxidoreductase subunit E.
    
  0.767
Your Current Organism:
Streptomyces guanduensis
NCBI taxonomy Id: 310781
Other names: CGMCC 4.2022, JCM 13274, NBRC 102070, S. guanduensis, Streptomyces guanduensis Xu et al. 2006, Streptomyces sp. 701, strain 701
Server load: low (14%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.