node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
SHK75574.1 | lipA | SAMN05216499_101559 | SAMN05216499_106324 | Ribonucleoside-diphosphate reductase alpha chain; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. | Lipoic acid synthetase; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives. | 0.663 |
SHL61105.1 | SHL87343.1 | SAMN05216499_105112 | SAMN05216499_106308 | Pyruvate dehydrogenase E2 component (dihydrolipoamide acetyltransferase). | Dihydrolipoamide dehydrogenase. | 0.996 |
SHL61105.1 | SHL87380.1 | SAMN05216499_105112 | SAMN05216499_106309 | Pyruvate dehydrogenase E2 component (dihydrolipoamide acetyltransferase). | 2-oxoglutarate dehydrogenase E2 component. | 0.483 |
SHL61105.1 | gcvH | SAMN05216499_105112 | SAMN05216499_113197 | Pyruvate dehydrogenase E2 component (dihydrolipoamide acetyltransferase). | Glycine cleavage system H protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. | 0.881 |
SHL61105.1 | gcvP | SAMN05216499_105112 | SAMN05216499_1093 | Pyruvate dehydrogenase E2 component (dihydrolipoamide acetyltransferase). | Glycine dehydrogenase (decarboxylating); The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. | 0.866 |
SHL61105.1 | lipA | SAMN05216499_105112 | SAMN05216499_106324 | Pyruvate dehydrogenase E2 component (dihydrolipoamide acetyltransferase). | Lipoic acid synthetase; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives. | 0.643 |
SHL61105.1 | lipB | SAMN05216499_105112 | SAMN05216499_106323 | Pyruvate dehydrogenase E2 component (dihydrolipoamide acetyltransferase). | Lipoyl(octanoyl) transferase; Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate- dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate. | 0.535 |
SHL87343.1 | SHL61105.1 | SAMN05216499_106308 | SAMN05216499_105112 | Dihydrolipoamide dehydrogenase. | Pyruvate dehydrogenase E2 component (dihydrolipoamide acetyltransferase). | 0.996 |
SHL87343.1 | SHL87380.1 | SAMN05216499_106308 | SAMN05216499_106309 | Dihydrolipoamide dehydrogenase. | 2-oxoglutarate dehydrogenase E2 component. | 0.999 |
SHL87343.1 | gcvH | SAMN05216499_106308 | SAMN05216499_113197 | Dihydrolipoamide dehydrogenase. | Glycine cleavage system H protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. | 0.968 |
SHL87343.1 | gcvP | SAMN05216499_106308 | SAMN05216499_1093 | Dihydrolipoamide dehydrogenase. | Glycine dehydrogenase (decarboxylating); The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. | 0.979 |
SHL87343.1 | lipA | SAMN05216499_106308 | SAMN05216499_106324 | Dihydrolipoamide dehydrogenase. | Lipoic acid synthetase; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives. | 0.656 |
SHL87343.1 | lipB | SAMN05216499_106308 | SAMN05216499_106323 | Dihydrolipoamide dehydrogenase. | Lipoyl(octanoyl) transferase; Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate- dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate. | 0.465 |
SHL87380.1 | SHL61105.1 | SAMN05216499_106309 | SAMN05216499_105112 | 2-oxoglutarate dehydrogenase E2 component. | Pyruvate dehydrogenase E2 component (dihydrolipoamide acetyltransferase). | 0.483 |
SHL87380.1 | SHL87343.1 | SAMN05216499_106309 | SAMN05216499_106308 | 2-oxoglutarate dehydrogenase E2 component. | Dihydrolipoamide dehydrogenase. | 0.999 |
SHL87380.1 | gcvH | SAMN05216499_106309 | SAMN05216499_113197 | 2-oxoglutarate dehydrogenase E2 component. | Glycine cleavage system H protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. | 0.885 |
SHL87380.1 | gcvP | SAMN05216499_106309 | SAMN05216499_1093 | 2-oxoglutarate dehydrogenase E2 component. | Glycine dehydrogenase (decarboxylating); The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. | 0.869 |
SHL87380.1 | lipA | SAMN05216499_106309 | SAMN05216499_106324 | 2-oxoglutarate dehydrogenase E2 component. | Lipoic acid synthetase; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives. | 0.677 |
SHL87380.1 | lipB | SAMN05216499_106309 | SAMN05216499_106323 | 2-oxoglutarate dehydrogenase E2 component. | Lipoyl(octanoyl) transferase; Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate- dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate. | 0.695 |
SHL87946.1 | SHL87982.1 | SAMN05216499_106325 | SAMN05216499_106326 | Hypothetical protein. | Protein of unknown function. | 0.829 |