STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SHM22031.1FMN-dependent dehydrogenase, includes L-lactate dehydrogenase and type II isopentenyl diphosphate isomerase. (396 aa)    
Predicted Functional Partners:
SHK91719.1
Glycolate oxidase.
  
 0.814
ackA
Acetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family.
     
 0.807
SHK93525.1
D-lactate dehydrogenase.
  
 0.806
SHL93118.1
FAD/FMN-containing dehydrogenase.
  
 0.806
SHN17669.1
FAD/FMN-containing dehydrogenase.
  
 0.806
SHK66398.1
Aldehyde dehydrogenase (acceptor).
 
 
 
  0.799
SHL44048.1
Benzaldehyde dehydrogenase (NAD+).
 
 
 
  0.799
SHN12032.1
Aldehyde dehydrogenase (NAD+); Belongs to the aldehyde dehydrogenase family.
 
 
 
  0.799
SHM61710.1
acetyl-CoA synthetase.
   
 
 0.797
acsA-2
Acetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family.
   
 
 0.797
Your Current Organism:
Streptomyces paucisporeus
NCBI taxonomy Id: 310782
Other names: CGMCC 4.2025, JCM 13276, NBRC 102072, S. paucisporeus, Streptomyces paucisporeus Xu et al. 2006
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