node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
SHM17259.1 | SHM17309.1 | SAMN05216499_10914 | SAMN05216499_10915 | Beta-glucosidase. | Pyridoxamine 5'-phosphate oxidase. | 0.469 |
SHM17309.1 | SHM17259.1 | SAMN05216499_10915 | SAMN05216499_10914 | Pyridoxamine 5'-phosphate oxidase. | Beta-glucosidase. | 0.469 |
SHM17309.1 | SHM17355.1 | SAMN05216499_10915 | SAMN05216499_10916 | Pyridoxamine 5'-phosphate oxidase. | Clp amino terminal domain-containing protein, pathogenicity island component. | 0.563 |
SHM17309.1 | SHM17397.1 | SAMN05216499_10915 | SAMN05216499_10917 | Pyridoxamine 5'-phosphate oxidase. | Threonine/homoserine efflux transporter RhtA. | 0.446 |
SHM17309.1 | SHM70207.1 | SAMN05216499_10915 | SAMN05216499_113127 | Pyridoxamine 5'-phosphate oxidase. | Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase. | 0.703 |
SHM17309.1 | SHM96378.1 | SAMN05216499_10915 | SAMN05216499_11754 | Pyridoxamine 5'-phosphate oxidase. | Pyridoxamine 5'-phosphate oxidase. | 0.734 |
SHM17309.1 | gcvP | SAMN05216499_10915 | SAMN05216499_1093 | Pyridoxamine 5'-phosphate oxidase. | Glycine dehydrogenase (decarboxylating); The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. | 0.414 |
SHM17309.1 | nnrD | SAMN05216499_10915 | SAMN05216499_101170 | Pyridoxamine 5'-phosphate oxidase. | yjeF C-terminal region, hydroxyethylthiazole kinase-related/yjeF N-terminal region; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specif [...] | 0.475 |
SHM17309.1 | pdxH | SAMN05216499_10915 | SAMN05216499_10731 | Pyridoxamine 5'-phosphate oxidase. | Pyridoxamine 5'-phosphate oxidase; Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP). | 0.841 |
SHM17309.1 | pdxS | SAMN05216499_10915 | SAMN05216499_111203 | Pyridoxamine 5'-phosphate oxidase. | Pyridoxal phosphate synthase yaaD subunit; Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5- phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively. Belongs to the PdxS/SNZ family. | 0.819 |
SHM17309.1 | pdxT | SAMN05216499_10915 | SAMN05216499_111204 | Pyridoxamine 5'-phosphate oxidase. | Pyridoxal phosphate synthase yaaE subunit; Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS. | 0.818 |
SHM17355.1 | SHM17309.1 | SAMN05216499_10916 | SAMN05216499_10915 | Clp amino terminal domain-containing protein, pathogenicity island component. | Pyridoxamine 5'-phosphate oxidase. | 0.563 |
SHM17355.1 | SHM17397.1 | SAMN05216499_10916 | SAMN05216499_10917 | Clp amino terminal domain-containing protein, pathogenicity island component. | Threonine/homoserine efflux transporter RhtA. | 0.843 |
SHM17397.1 | SHM17309.1 | SAMN05216499_10917 | SAMN05216499_10915 | Threonine/homoserine efflux transporter RhtA. | Pyridoxamine 5'-phosphate oxidase. | 0.446 |
SHM17397.1 | SHM17355.1 | SAMN05216499_10917 | SAMN05216499_10916 | Threonine/homoserine efflux transporter RhtA. | Clp amino terminal domain-containing protein, pathogenicity island component. | 0.843 |
SHM70207.1 | SHM17309.1 | SAMN05216499_113127 | SAMN05216499_10915 | Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase. | Pyridoxamine 5'-phosphate oxidase. | 0.703 |
SHM70207.1 | SHM96378.1 | SAMN05216499_113127 | SAMN05216499_11754 | Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase. | Pyridoxamine 5'-phosphate oxidase. | 0.703 |
SHM70207.1 | pdxH | SAMN05216499_113127 | SAMN05216499_10731 | Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase. | Pyridoxamine 5'-phosphate oxidase; Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP). | 0.703 |
SHM70207.1 | pdxS | SAMN05216499_113127 | SAMN05216499_111203 | Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase. | Pyridoxal phosphate synthase yaaD subunit; Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5- phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively. Belongs to the PdxS/SNZ family. | 0.850 |
SHM70207.1 | pdxT | SAMN05216499_113127 | SAMN05216499_111204 | Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase. | Pyridoxal phosphate synthase yaaE subunit; Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS. | 0.847 |