node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
SHK77416.1 | SHL82262.1 | SAMN05216499_101602 | SAMN05216499_106163 | 2-oxoglutarate dehydrogenase E1 component. | Glutamate synthase (NADH) large subunit. | 0.978 |
SHK77416.1 | SHL87343.1 | SAMN05216499_101602 | SAMN05216499_106308 | 2-oxoglutarate dehydrogenase E1 component. | Dihydrolipoamide dehydrogenase. | 0.999 |
SHK77416.1 | SHM91665.1 | SAMN05216499_101602 | SAMN05216499_11688 | 2-oxoglutarate dehydrogenase E1 component. | Glycine hydroxymethyltransferase. | 0.683 |
SHK77416.1 | SHN15618.1 | SAMN05216499_101602 | SAMN05216499_12326 | 2-oxoglutarate dehydrogenase E1 component. | 2-oxoglutarate dehydrogenase E1 component. | 0.999 |
SHK77416.1 | gcvH | SAMN05216499_101602 | SAMN05216499_113197 | 2-oxoglutarate dehydrogenase E1 component. | Glycine cleavage system H protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. | 0.977 |
SHK77416.1 | gcvP | SAMN05216499_101602 | SAMN05216499_1093 | 2-oxoglutarate dehydrogenase E1 component. | Glycine dehydrogenase (decarboxylating); The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. | 0.991 |
SHK77416.1 | gcvT | SAMN05216499_101602 | SAMN05216499_113196 | 2-oxoglutarate dehydrogenase E1 component. | Aminomethyltransferase; The glycine cleavage system catalyzes the degradation of glycine. | 0.952 |
SHK77416.1 | glyA | SAMN05216499_101602 | SAMN05216499_104161 | 2-oxoglutarate dehydrogenase E1 component. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.683 |
SHK77416.1 | glyA-2 | SAMN05216499_101602 | SAMN05216499_113198 | 2-oxoglutarate dehydrogenase E1 component. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.683 |
SHL82262.1 | SHK77416.1 | SAMN05216499_106163 | SAMN05216499_101602 | Glutamate synthase (NADH) large subunit. | 2-oxoglutarate dehydrogenase E1 component. | 0.978 |
SHL82262.1 | SHL87343.1 | SAMN05216499_106163 | SAMN05216499_106308 | Glutamate synthase (NADH) large subunit. | Dihydrolipoamide dehydrogenase. | 0.951 |
SHL82262.1 | SHM91665.1 | SAMN05216499_106163 | SAMN05216499_11688 | Glutamate synthase (NADH) large subunit. | Glycine hydroxymethyltransferase. | 0.909 |
SHL82262.1 | SHN15618.1 | SAMN05216499_106163 | SAMN05216499_12326 | Glutamate synthase (NADH) large subunit. | 2-oxoglutarate dehydrogenase E1 component. | 0.978 |
SHL82262.1 | gcvH | SAMN05216499_106163 | SAMN05216499_113197 | Glutamate synthase (NADH) large subunit. | Glycine cleavage system H protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. | 0.956 |
SHL82262.1 | gcvP | SAMN05216499_106163 | SAMN05216499_1093 | Glutamate synthase (NADH) large subunit. | Glycine dehydrogenase (decarboxylating); The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. | 0.993 |
SHL82262.1 | gcvT | SAMN05216499_106163 | SAMN05216499_113196 | Glutamate synthase (NADH) large subunit. | Aminomethyltransferase; The glycine cleavage system catalyzes the degradation of glycine. | 0.961 |
SHL82262.1 | glyA | SAMN05216499_106163 | SAMN05216499_104161 | Glutamate synthase (NADH) large subunit. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.909 |
SHL82262.1 | glyA-2 | SAMN05216499_106163 | SAMN05216499_113198 | Glutamate synthase (NADH) large subunit. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.909 |
SHL82262.1 | purD | SAMN05216499_106163 | SAMN05216499_103138 | Glutamate synthase (NADH) large subunit. | Phosphoribosylamine--glycine ligase; Belongs to the GARS family. | 0.542 |
SHL87343.1 | SHK77416.1 | SAMN05216499_106308 | SAMN05216499_101602 | Dihydrolipoamide dehydrogenase. | 2-oxoglutarate dehydrogenase E1 component. | 0.999 |