node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
SHL80347.1 | pdxS | SAMN05216499_106111 | SAMN05216499_111203 | Transketolase; Belongs to the transketolase family. | Pyridoxal phosphate synthase yaaD subunit; Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5- phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively. Belongs to the PdxS/SNZ family. | 0.917 |
SHL80347.1 | prs | SAMN05216499_106111 | SAMN05216499_107165 | Transketolase; Belongs to the transketolase family. | Ribose-phosphate pyrophosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily. | 0.959 |
SHL80347.1 | rbsK | SAMN05216499_106111 | SAMN05216499_109109 | Transketolase; Belongs to the transketolase family. | Ribokinase; Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway. | 0.928 |
SHL80347.1 | tal | SAMN05216499_106111 | SAMN05216499_106112 | Transketolase; Belongs to the transketolase family. | Transaldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway; Belongs to the transaldolase family. Type 2 subfamily. | 0.999 |
SHM50851.1 | pdxS | SAMN05216499_111205 | SAMN05216499_111203 | DNA-binding regulatory protein, YebC/PmpR family. | Pyridoxal phosphate synthase yaaD subunit; Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5- phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively. Belongs to the PdxS/SNZ family. | 0.937 |
SHM50851.1 | pdxT | SAMN05216499_111205 | SAMN05216499_111204 | DNA-binding regulatory protein, YebC/PmpR family. | Pyridoxal phosphate synthase yaaE subunit; Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS. | 0.937 |
SHM58937.1 | pdxS | SAMN05216499_112110 | SAMN05216499_111203 | Transketolase. | Pyridoxal phosphate synthase yaaD subunit; Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5- phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively. Belongs to the PdxS/SNZ family. | 0.917 |
SHM58937.1 | prs | SAMN05216499_112110 | SAMN05216499_107165 | Transketolase. | Ribose-phosphate pyrophosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily. | 0.959 |
SHM58937.1 | rbsK | SAMN05216499_112110 | SAMN05216499_109109 | Transketolase. | Ribokinase; Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway. | 0.928 |
SHM58937.1 | tal | SAMN05216499_112110 | SAMN05216499_106112 | Transketolase. | Transaldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway; Belongs to the transaldolase family. Type 2 subfamily. | 0.999 |
SHM70207.1 | SHM96378.1 | SAMN05216499_113127 | SAMN05216499_11754 | Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase. | Pyridoxamine 5'-phosphate oxidase. | 0.703 |
SHM70207.1 | pdxH | SAMN05216499_113127 | SAMN05216499_10731 | Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase. | Pyridoxamine 5'-phosphate oxidase; Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP). | 0.703 |
SHM70207.1 | pdxS | SAMN05216499_113127 | SAMN05216499_111203 | Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase. | Pyridoxal phosphate synthase yaaD subunit; Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5- phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively. Belongs to the PdxS/SNZ family. | 0.850 |
SHM70207.1 | pdxT | SAMN05216499_113127 | SAMN05216499_111204 | Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase. | Pyridoxal phosphate synthase yaaE subunit; Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS. | 0.847 |
SHM96378.1 | SHM70207.1 | SAMN05216499_11754 | SAMN05216499_113127 | Pyridoxamine 5'-phosphate oxidase. | Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase. | 0.703 |
SHM96378.1 | pdxS | SAMN05216499_11754 | SAMN05216499_111203 | Pyridoxamine 5'-phosphate oxidase. | Pyridoxal phosphate synthase yaaD subunit; Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5- phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively. Belongs to the PdxS/SNZ family. | 0.842 |
SHM96378.1 | pdxT | SAMN05216499_11754 | SAMN05216499_111204 | Pyridoxamine 5'-phosphate oxidase. | Pyridoxal phosphate synthase yaaE subunit; Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS. | 0.862 |
pdxH | SHM70207.1 | SAMN05216499_10731 | SAMN05216499_113127 | Pyridoxamine 5'-phosphate oxidase; Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP). | Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase. | 0.703 |
pdxH | pdxS | SAMN05216499_10731 | SAMN05216499_111203 | Pyridoxamine 5'-phosphate oxidase; Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP). | Pyridoxal phosphate synthase yaaD subunit; Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5- phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively. Belongs to the PdxS/SNZ family. | 0.956 |
pdxH | pdxT | SAMN05216499_10731 | SAMN05216499_111204 | Pyridoxamine 5'-phosphate oxidase; Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP). | Pyridoxal phosphate synthase yaaE subunit; Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS. | 0.955 |