STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SHM56841.1Dihydrofolate reductase. (181 aa)    
Predicted Functional Partners:
SHM56888.1
Helix-turn-helix domain-containing protein.
       0.773
SHM56803.1
Uncharacterized conserved protein YndB, AHSA1/START domain.
       0.710
SHM45064.1
Methionine synthase (B12-dependent); Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
    
 0.706
SHM56767.1
Alpha/beta hydrolase family protein.
       0.572
SHM56921.1
Hypothetical protein.
       0.535
SHN15669.1
Dihydrofolate reductase.
 
     0.472
SHM11780.1
Acyl transferase domain-containing protein.
  
 
 0.469
SHN38408.1
Alcohol dehydrogenase GroES-like domain-containing protein.
  
 
 0.469
SHM83246.1
Phosphopantetheine attachment site.
  
 
 0.468
SHM68038.1
Glyoxalase superfamily enzyme, possibly 3-demethylubiquinone-9 3-methyltransferase.
 
    0.465
Your Current Organism:
Streptomyces paucisporeus
NCBI taxonomy Id: 310782
Other names: CGMCC 4.2025, JCM 13276, NBRC 102072, S. paucisporeus, Streptomyces paucisporeus Xu et al. 2006
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.