STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SHM89991.1Regulator of chromosome condensation (RCC1) repeat-containing protein. (90 aa)    
Predicted Functional Partners:
SHK55222.1
NADH dehydrogenase subunit M.
    
 
 0.928
SHN21300.1
NADH dehydrogenase subunit M.
    
 
 0.928
SHN31429.1
Carbonic anhydrase.
    
   0.915
SHN08145.1
Protein tyrosine phosphatase.
   
   0.891
SHN16752.1
Protein-tyrosine phosphatase.
   
   0.891
SHN30866.1
Protein-tyrosine phosphatase.
   
   0.891
SHL83178.1
Hypothetical protein.
  
 
  0.842
secY
Protein translocase subunit secY/sec61 alpha; The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.
    
   0.766
SHM38832.1
FHA domain-containing protein.
 
 
  0.744
SHN01314.1
ring-1,2-phenylacetyl-CoA epoxidase subunit PaaE.
    
   0.732
Your Current Organism:
Streptomyces paucisporeus
NCBI taxonomy Id: 310782
Other names: CGMCC 4.2025, JCM 13276, NBRC 102072, S. paucisporeus, Streptomyces paucisporeus Xu et al. 2006
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.