node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
SHK76876.1 | SHM89666.1 | SAMN05216499_101590 | SAMN05216499_11623 | Molecular chaperone DnaK. | Molecular chaperone DnaK. | 0.508 |
SHK76876.1 | clpB | SAMN05216499_101590 | SAMN05216499_117124 | Molecular chaperone DnaK. | ATP-dependent Clp protease ATP-binding subunit ClpB; Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE; Belongs to the ClpA/ClpB family. | 0.911 |
SHK76876.1 | clpP | SAMN05216499_101590 | SAMN05216499_102248 | Molecular chaperone DnaK. | ATP-dependent Clp protease proteolytic subunit ClpP; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family. | 0.628 |
SHK76876.1 | clpP-2 | SAMN05216499_101590 | SAMN05216499_102249 | Molecular chaperone DnaK. | ATP-dependent Clp protease proteolytic subunit ClpP; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family. | 0.628 |
SHK76876.1 | clpP-3 | SAMN05216499_101590 | SAMN05216499_12853 | Molecular chaperone DnaK. | ATP-dependent Clp protease, protease subunit; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family. | 0.628 |
SHK76876.1 | clpS | SAMN05216499_101590 | SAMN05216499_10279 | Molecular chaperone DnaK. | ATP-dependent Clp protease adaptor protein ClpS; Involved in the modulation of the specificity of the ClpAP- mediated ATP-dependent protein degradation; Belongs to the ClpS family. | 0.476 |
SHK76876.1 | dnaJ-2 | SAMN05216499_101590 | SAMN05216499_117121 | Molecular chaperone DnaK. | Molecular chaperone DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, [...] | 0.989 |
SHK76876.1 | dnaK | SAMN05216499_101590 | SAMN05216499_117119 | Molecular chaperone DnaK. | Molecular chaperone DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family. | 0.465 |
SHK76876.1 | dnaK-2 | SAMN05216499_101590 | SAMN05216499_13147 | Molecular chaperone DnaK. | Molecular chaperone DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family. | 0.477 |
SHK76876.1 | grpE | SAMN05216499_101590 | SAMN05216499_117120 | Molecular chaperone DnaK. | Molecular chaperone GrpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP [...] | 0.984 |
SHM89666.1 | SHK76876.1 | SAMN05216499_11623 | SAMN05216499_101590 | Molecular chaperone DnaK. | Molecular chaperone DnaK. | 0.508 |
SHM89666.1 | clpB | SAMN05216499_11623 | SAMN05216499_117124 | Molecular chaperone DnaK. | ATP-dependent Clp protease ATP-binding subunit ClpB; Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE; Belongs to the ClpA/ClpB family. | 0.950 |
SHM89666.1 | clpP | SAMN05216499_11623 | SAMN05216499_102248 | Molecular chaperone DnaK. | ATP-dependent Clp protease proteolytic subunit ClpP; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family. | 0.684 |
SHM89666.1 | clpP-2 | SAMN05216499_11623 | SAMN05216499_102249 | Molecular chaperone DnaK. | ATP-dependent Clp protease proteolytic subunit ClpP; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family. | 0.626 |
SHM89666.1 | clpP-3 | SAMN05216499_11623 | SAMN05216499_12853 | Molecular chaperone DnaK. | ATP-dependent Clp protease, protease subunit; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family. | 0.626 |
SHM89666.1 | dnaJ-2 | SAMN05216499_11623 | SAMN05216499_117121 | Molecular chaperone DnaK. | Molecular chaperone DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, [...] | 0.980 |
SHM89666.1 | grpE | SAMN05216499_11623 | SAMN05216499_117120 | Molecular chaperone DnaK. | Molecular chaperone GrpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP [...] | 0.984 |
clpB | SHK76876.1 | SAMN05216499_117124 | SAMN05216499_101590 | ATP-dependent Clp protease ATP-binding subunit ClpB; Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE; Belongs to the ClpA/ClpB family. | Molecular chaperone DnaK. | 0.911 |
clpB | SHM89666.1 | SAMN05216499_117124 | SAMN05216499_11623 | ATP-dependent Clp protease ATP-binding subunit ClpB; Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE; Belongs to the ClpA/ClpB family. | Molecular chaperone DnaK. | 0.950 |
clpB | clpP | SAMN05216499_117124 | SAMN05216499_102248 | ATP-dependent Clp protease ATP-binding subunit ClpB; Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE; Belongs to the ClpA/ClpB family. | ATP-dependent Clp protease proteolytic subunit ClpP; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family. | 0.939 |