STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SHM94961.1Transcriptional regulator, LacI family. (353 aa)    
Predicted Functional Partners:
SHL82262.1
Glutamate synthase (NADH) large subunit.
    
 
 0.856
SHN19873.1
Phosphocarrier protein HPr.
 
 
 
 0.654
guaA
GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP.
    
   0.551
guaB
Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
    
   0.527
pheT
phenylalanyl-tRNA synthetase beta subunit; Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
    
   0.527
ribBA
GTP cyclohydrolase II /3,4-dihydroxy-2-butanone 4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the C-terminal section; belongs to the GTP cyclohydrolase II family.
    
   0.527
SHM11972.1
Amino acid adenylation domain-containing protein.
    
   0.510
SHM86439.1
Non-ribosomal peptide synthase domain TIGR01720/amino acid adenylation domain-containing protein.
    
   0.510
SHM94936.1
Methane oxygenase PmoA.
       0.494
SHM20756.1
Thioredoxin reductase (NADPH).
    
 
 0.478
Your Current Organism:
Streptomyces paucisporeus
NCBI taxonomy Id: 310782
Other names: CGMCC 4.2025, JCM 13276, NBRC 102072, S. paucisporeus, Streptomyces paucisporeus Xu et al. 2006
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