STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SHN04259.1RNA polymerase sigma-B factor; Belongs to the sigma-70 factor family. (300 aa)    
Predicted Functional Partners:
SHN14041.1
Hypothetical protein.
    
 
 0.876
rpoB
DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
  
 
 
 0.852
SHN25216.1
Signal transduction histidine kinase.
  
  
 0.820
rpoC
DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
 
 0.808
SHM07287.1
PAS/PAC sensor hybrid histidine kinase.
  
 
 0.759
SHN04327.1
Serine phosphatase RsbU, regulator of sigma subunit.
  
 
 0.730
SHN29961.1
Serine phosphatase RsbU, regulator of sigma subunit.
 
 
 0.720
rpoA
DNA-directed RNA polymerase subunit alpha; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
  
 
 
 0.711
SHK76269.1
Serine/threonine-protein kinase RsbW.
 
   0.711
SHN25209.1
PAS domain S-box-containing protein.
 
 
 0.697
Your Current Organism:
Streptomyces paucisporeus
NCBI taxonomy Id: 310782
Other names: CGMCC 4.2025, JCM 13276, NBRC 102072, S. paucisporeus, Streptomyces paucisporeus Xu et al. 2006
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.