node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
SHK73858.1 | SHK74000.1 | SAMN05216499_101514 | SAMN05216499_101518 | UvrD-like helicase C-terminal domain-containing protein; Belongs to the helicase family. UvrD subfamily. | DNA helicase-2 / ATP-dependent DNA helicase PcrA. | 0.999 |
SHK73858.1 | SHL64433.1 | SAMN05216499_101514 | SAMN05216499_105191 | UvrD-like helicase C-terminal domain-containing protein; Belongs to the helicase family. UvrD subfamily. | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | 0.937 |
SHK73858.1 | SHN35608.1 | SAMN05216499_101514 | SAMN05216499_1443 | UvrD-like helicase C-terminal domain-containing protein; Belongs to the helicase family. UvrD subfamily. | Conjugative relaxase domain-containing protein, TrwC/TraI family. | 0.517 |
SHK73858.1 | topA | SAMN05216499_101514 | SAMN05216499_13636 | UvrD-like helicase C-terminal domain-containing protein; Belongs to the helicase family. UvrD subfamily. | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...] | 0.787 |
SHK74000.1 | SHK73858.1 | SAMN05216499_101518 | SAMN05216499_101514 | DNA helicase-2 / ATP-dependent DNA helicase PcrA. | UvrD-like helicase C-terminal domain-containing protein; Belongs to the helicase family. UvrD subfamily. | 0.999 |
SHK74000.1 | SHL64433.1 | SAMN05216499_101518 | SAMN05216499_105191 | DNA helicase-2 / ATP-dependent DNA helicase PcrA. | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | 0.999 |
SHK74000.1 | SHN35608.1 | SAMN05216499_101518 | SAMN05216499_1443 | DNA helicase-2 / ATP-dependent DNA helicase PcrA. | Conjugative relaxase domain-containing protein, TrwC/TraI family. | 0.938 |
SHK74000.1 | topA | SAMN05216499_101518 | SAMN05216499_13636 | DNA helicase-2 / ATP-dependent DNA helicase PcrA. | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...] | 0.999 |
SHK74000.1 | truB | SAMN05216499_101518 | SAMN05216499_11335 | DNA helicase-2 / ATP-dependent DNA helicase PcrA. | tRNA pseudouridine55 synthase; Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs; Belongs to the pseudouridine synthase TruB family. Type 1 subfamily. | 0.472 |
SHL64433.1 | SHK73858.1 | SAMN05216499_105191 | SAMN05216499_101514 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | UvrD-like helicase C-terminal domain-containing protein; Belongs to the helicase family. UvrD subfamily. | 0.937 |
SHL64433.1 | SHK74000.1 | SAMN05216499_105191 | SAMN05216499_101518 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | DNA helicase-2 / ATP-dependent DNA helicase PcrA. | 0.999 |
SHL64433.1 | SHN35608.1 | SAMN05216499_105191 | SAMN05216499_1443 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | Conjugative relaxase domain-containing protein, TrwC/TraI family. | 0.789 |
SHL64433.1 | topA | SAMN05216499_105191 | SAMN05216499_13636 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...] | 0.943 |
SHN13531.1 | SHN13545.1 | SAMN05216499_12211 | SAMN05216499_12212 | Hypothetical protein. | AAA-like domain-containing protein. | 0.974 |
SHN13531.1 | SHN13569.1 | SAMN05216499_12211 | SAMN05216499_12214 | Hypothetical protein. | Hypothetical protein. | 0.964 |
SHN13531.1 | SHN22805.1 | SAMN05216499_12211 | SAMN05216499_12741 | Hypothetical protein. | Hypothetical protein. | 0.861 |
SHN13531.1 | SHN22824.1 | SAMN05216499_12211 | SAMN05216499_12743 | Hypothetical protein. | Hypothetical protein. | 0.862 |
SHN13531.1 | SHN35608.1 | SAMN05216499_12211 | SAMN05216499_1443 | Hypothetical protein. | Conjugative relaxase domain-containing protein, TrwC/TraI family. | 0.748 |
SHN13531.1 | topA | SAMN05216499_12211 | SAMN05216499_13636 | Hypothetical protein. | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...] | 0.460 |
SHN13545.1 | SHN13531.1 | SAMN05216499_12212 | SAMN05216499_12211 | AAA-like domain-containing protein. | Hypothetical protein. | 0.974 |