node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Avi_3275 | ftsW | Avi_3275 | Avi_2892 | Conserved hypothetical protein. | Cell division protein; Belongs to the SEDS family. | 0.558 |
Avi_3275 | murD | Avi_3275 | Avi_2893 | Conserved hypothetical protein. | UDP-N-acetylmuramoylalanine--D-glutamate ligase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family. | 0.456 |
Avi_3275 | murI | Avi_3275 | Avi_1916 | Conserved hypothetical protein. | Glutamate racemase; Provides the (R)-glutamate required for cell wall biosynthesis. | 0.510 |
ftsW | Avi_3275 | Avi_2892 | Avi_3275 | Cell division protein; Belongs to the SEDS family. | Conserved hypothetical protein. | 0.558 |
ftsW | murD | Avi_2892 | Avi_2893 | Cell division protein; Belongs to the SEDS family. | UDP-N-acetylmuramoylalanine--D-glutamate ligase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family. | 0.982 |
ftsW | murG | Avi_2892 | Avi_2891 | Cell division protein; Belongs to the SEDS family. | Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase; Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II); Belongs to the glycosyltransferase 28 family. MurG subfamily. | 0.984 |
ftsW | murI | Avi_2892 | Avi_1916 | Cell division protein; Belongs to the SEDS family. | Glutamate racemase; Provides the (R)-glutamate required for cell wall biosynthesis. | 0.515 |
glsA | gltB | Avi_1928 | Avi_3734 | Glutaminase A; Belongs to the glutaminase family. | Glutamate synthase large subunit. | 0.947 |
glsA | murD | Avi_1928 | Avi_2893 | Glutaminase A; Belongs to the glutaminase family. | UDP-N-acetylmuramoylalanine--D-glutamate ligase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family. | 0.902 |
glsA | murI | Avi_1928 | Avi_1916 | Glutaminase A; Belongs to the glutaminase family. | Glutamate racemase; Provides the (R)-glutamate required for cell wall biosynthesis. | 0.926 |
glsA | purQ | Avi_1928 | Avi_1902 | Glutaminase A; Belongs to the glutaminase family. | Phosphoribosylformylglycinamidine synthase I; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist i [...] | 0.900 |
gltB | glsA | Avi_3734 | Avi_1928 | Glutamate synthase large subunit. | Glutaminase A; Belongs to the glutaminase family. | 0.947 |
gltB | icdA | Avi_3734 | Avi_1913 | Glutamate synthase large subunit. | Isocitrate dehydrogenase; Belongs to the isocitrate and isopropylmalate dehydrogenases family. | 0.907 |
gltB | murD | Avi_3734 | Avi_2893 | Glutamate synthase large subunit. | UDP-N-acetylmuramoylalanine--D-glutamate ligase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family. | 0.495 |
gltB | murI | Avi_3734 | Avi_1916 | Glutamate synthase large subunit. | Glutamate racemase; Provides the (R)-glutamate required for cell wall biosynthesis. | 0.578 |
gltB | purQ | Avi_3734 | Avi_1902 | Glutamate synthase large subunit. | Phosphoribosylformylglycinamidine synthase I; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist i [...] | 0.901 |
gltB | topA | Avi_3734 | Avi_1756 | Glutamate synthase large subunit. | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...] | 0.751 |
icdA | gltB | Avi_1913 | Avi_3734 | Isocitrate dehydrogenase; Belongs to the isocitrate and isopropylmalate dehydrogenases family. | Glutamate synthase large subunit. | 0.907 |
icdA | lasT | Avi_1913 | Avi_1915 | Isocitrate dehydrogenase; Belongs to the isocitrate and isopropylmalate dehydrogenases family. | tRNA/rRNA methyltransferase; Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA. | 0.548 |
icdA | murI | Avi_1913 | Avi_1916 | Isocitrate dehydrogenase; Belongs to the isocitrate and isopropylmalate dehydrogenases family. | Glutamate racemase; Provides the (R)-glutamate required for cell wall biosynthesis. | 0.565 |