STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
sucB2-oxoglutarate dehydrogenase, E2 component, dihydrolipoamide succinyltransferase; E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2- oxoglutarate to succinyl-CoA and CO(2). (412 aa)    
Predicted Functional Partners:
sucA
2-oxoglutarate dehydrogenase, E1 component.
 0.999
bkdA2
2-oxoisovalerate dehydrogenase beta subunit protein.
 
 0.998
lpdA-2
Dihydrolipoamide dehydrogenase.
 0.998
lpdA
Dihydrolipoamide dehydrogenase.
 0.996
sucD
succinyl-CoA synthetase alpha subunit protein; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.
 
 0.989
sucC
succinyl-CoA synthetase beta subunit protein; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.
 
 0.988
pdhA2
Pyruvate dehydrogenase beta subunit protein; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2.
0.964
pdhA1
Pyruvate dehydrogenase alpha subunit protein; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).
 
 0.960
gor
Glutathione-disulfide reductase; Maintains high levels of reduced glutathione.
 0.930
Arad_2151
Pyridine nucleotide transhydrogenase protein.
 0.912
Your Current Organism:
Agrobacterium radiobacter
NCBI taxonomy Id: 311403
Other names: A. radiobacter K84, Agrobacterium radiobacter K84, Agrobacterium radiobacter str. K84, Agrobacterium radiobacter strain K84, Agrobacterium rhizogenes K84, Agrobacterium tumefaciens K84, Rhizobium radiobacter K84
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