node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Arad_0139 | Arad_4527 | Arad_0139 | Arad_4527 | Transcriptional regulator protein. | Conserved hypothetical protein. | 0.441 |
Arad_1727 | Arad_4527 | Arad_1727 | Arad_4527 | DNA replication initiation ATPase protein; Belongs to the DnaA family. | Conserved hypothetical protein. | 0.589 |
Arad_1727 | dnaA | Arad_1727 | Arad_0601 | DNA replication initiation ATPase protein; Belongs to the DnaA family. | Chromosomal replication initiator protein DnaA; Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'- TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids. Belongs to the DnaA family. | 0.529 |
Arad_1727 | dnaX | Arad_1727 | Arad_0186 | DNA replication initiation ATPase protein; Belongs to the DnaA family. | DNA polymerase III; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. | 0.557 |
Arad_1727 | polA | Arad_1727 | Arad_0271 | DNA replication initiation ATPase protein; Belongs to the DnaA family. | DNA-directed DNA polymerase; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.416 |
Arad_1727 | topA | Arad_1727 | Arad_1891 | DNA replication initiation ATPase protein; Belongs to the DnaA family. | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...] | 0.538 |
Arad_2253 | Arad_4527 | Arad_2253 | Arad_4527 | Conserved hypothetical membrane protein. | Conserved hypothetical protein. | 0.494 |
Arad_4401 | Arad_4527 | Arad_4401 | Arad_4527 | Conserved hypothetical protein. | Conserved hypothetical protein. | 0.446 |
Arad_4527 | Arad_0139 | Arad_4527 | Arad_0139 | Conserved hypothetical protein. | Transcriptional regulator protein. | 0.441 |
Arad_4527 | Arad_1727 | Arad_4527 | Arad_1727 | Conserved hypothetical protein. | DNA replication initiation ATPase protein; Belongs to the DnaA family. | 0.589 |
Arad_4527 | Arad_2253 | Arad_4527 | Arad_2253 | Conserved hypothetical protein. | Conserved hypothetical membrane protein. | 0.494 |
Arad_4527 | Arad_4401 | Arad_4527 | Arad_4401 | Conserved hypothetical protein. | Conserved hypothetical protein. | 0.446 |
Arad_4527 | dnaA | Arad_4527 | Arad_0601 | Conserved hypothetical protein. | Chromosomal replication initiator protein DnaA; Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'- TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids. Belongs to the DnaA family. | 0.589 |
Arad_4527 | dnaG | Arad_4527 | Arad_3123 | Conserved hypothetical protein. | DNA primase protein; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. | 0.787 |
Arad_4527 | dnaX | Arad_4527 | Arad_0186 | Conserved hypothetical protein. | DNA polymerase III; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. | 0.546 |
Arad_4527 | polA | Arad_4527 | Arad_0271 | Conserved hypothetical protein. | DNA-directed DNA polymerase; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.526 |
Arad_4527 | ssb | Arad_4527 | Arad_2379 | Conserved hypothetical protein. | Single-strand DNA binding protein; Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism. | 0.443 |
Arad_4527 | topA | Arad_4527 | Arad_1891 | Conserved hypothetical protein. | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...] | 0.461 |
dnaA | Arad_1727 | Arad_0601 | Arad_1727 | Chromosomal replication initiator protein DnaA; Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'- TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids. Belongs to the DnaA family. | DNA replication initiation ATPase protein; Belongs to the DnaA family. | 0.529 |
dnaA | Arad_4527 | Arad_0601 | Arad_4527 | Chromosomal replication initiator protein DnaA; Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'- TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids. Belongs to the DnaA family. | Conserved hypothetical protein. | 0.589 |