Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
dnaKMolecular chaperone DnaK; Acts as a chaperone. (592 aa)    
Predicted Functional Partners:
BAJ49883.1
Molecular chaperone GrpE; Belongs to the GrpE family.
 
 0.999
BAJ51183.1
Heat shock protein DnaJ-like.
  
 0.999
BAJ49881.1
Molecular chaperone DnaJ.
   
 0.995
BAJ49985.1
Nitrogen fixation protein NifU.
  
 0.974
BAJ49998.1
Thermosome subunit alpha; Belongs to the TCP-1 chaperonin family.
  
 0.956
BAJ50531.1
Thermosome alpha subunit; Belongs to the TCP-1 chaperonin family.
  
 0.956
BAJ51261.1
Thermosome beta subunit; Belongs to the TCP-1 chaperonin family.
  
 0.956
fusA
Elongation factor EF-2; Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
 
 
 0.914
gap
Glyceraldehyde-3-phosphate dehydrogenase.
  
 0.909
BAJ50184.1
Small subunit ribosomal protein S2; Belongs to the universal ribosomal protein uS2 family.
  
 0.900
Your Current Organism:
Caldiarchaeum subterraneum
NCBI taxonomy Id: 311458
Other names: C. Caldiarchaeum subterraneum, Candidatus Caldiarchaeum subterraneum, uncultured crenarchaeote 10-H-08
Server load: medium (52%) [HD]