Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
BAJ49883.1Molecular chaperone GrpE; Belongs to the GrpE family. (164 aa)    
Predicted Functional Partners:
dnaK
Molecular chaperone DnaK; Acts as a chaperone.
 
 0.999
BAJ51183.1
Heat shock protein DnaJ-like.
  
 
 0.995
BAJ49881.1
Molecular chaperone DnaJ.
 
   
 0.953
BAJ49998.1
Thermosome subunit alpha; Belongs to the TCP-1 chaperonin family.
  
 0.932
BAJ50531.1
Thermosome alpha subunit; Belongs to the TCP-1 chaperonin family.
  
 0.932
BAJ51261.1
Thermosome beta subunit; Belongs to the TCP-1 chaperonin family.
  
 0.932
dnaG
DNA primase; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. Also part of the exosome, which is a complex involved in RNA degradation. Acts as a poly(A)-binding protein that enhances the interaction between heteropolymeric, adenine-rich transcripts and the exosome.
  
  
 0.692
eif1a
Translation initiation factor eIF-1A; Seems to be required for maximal rate of protein biosynthesis. Enhances ribosome dissociation into subunits and stabilizes the binding of the initiator Met-tRNA(I) to 40 S ribosomal subunits.
  
  
 0.648
hisB
Imidazoleglycerol-phosphate dehydratase.
     
 0.627
BAJ50968.1
ATP phosphoribosyltransferase.
  
  
 0.617
Your Current Organism:
Caldiarchaeum subterraneum
NCBI taxonomy Id: 311458
Other names: C. Caldiarchaeum subterraneum, Candidatus Caldiarchaeum subterraneum, uncultured crenarchaeote 10-H-08
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