Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
BAJ49948.1Conserved hypothetical protein; KH domain, putative RNA-processing protein. (201 aa)    
Predicted Functional Partners:
BAJ50141.1
pre-mRNA processing ribonucleoprotein, binding region.
  
 
 0.980
nep1
Ribosome biogenesis protein; Methyltransferase involved in ribosomal biogenesis. Specifically catalyzes the N1-methylation of the pseudouridine corresponding to position 914 in M.jannaschii 16S rRNA.
  
 0.979
rps4
Small subunit ribosomal protein S4; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
   
 0.979
rps6e
Small subunit ribosomal protein S6e; Belongs to the eukaryotic ribosomal protein eS6 family.
  
 0.978
BAJ50294.1
Conserved hypothetical protein.
   
 0.977
rps11
Small subunit ribosomal protein S11; Located on the platform of the 30S subunit. Belongs to the universal ribosomal protein uS11 family.
  
 0.962
flpA
Fibrillarin-like pre-rRNA processing protein; Involved in pre-rRNA and tRNA processing. Utilizes the methyl donor S-adenosyl-L-methionine to catalyze the site-specific 2'-hydroxyl methylation of ribose moieties in rRNA and tRNA. Site specificity is provided by a guide RNA that base pairs with the substrate. Methylation occurs at a characteristic distance from the sequence involved in base pairing with the guide RNA; Belongs to the methyltransferase superfamily. Fibrillarin family.
  
 0.949
rpl10
Large subunit ribosomal protein L10; Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors. Belongs to the universal ribosomal protein uL10 family.
  
 
 0.948
rps3ae
Small subunit ribosomal protein S3Ae; Belongs to the eukaryotic ribosomal protein eS1 family.
 
  0.947
BAJ49949.1
RIO kinase 1.
 
  
 0.944
Your Current Organism:
Caldiarchaeum subterraneum
NCBI taxonomy Id: 311458
Other names: C. Caldiarchaeum subterraneum, Candidatus Caldiarchaeum subterraneum, uncultured crenarchaeote 10-H-08
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