STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
BAJ50056.1DNA topoisomerase III. (606 aa)    
Predicted Functional Partners:
BAJ51190.1
ERCC4 domain-containing protein.
    
 0.925
rpoA2
DNA-directed RNA polymerase subunit A; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
 
 
 0.869
rpoK
DNA-directed RNA polymerase subunit K; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal RpoK/eukaryotic RPB6 RNA polymerase subunit family.
 
 
 
 0.868
BAJ49872.1
Replication factor C small subunit.
 
 0.837
BAJ51472.1
Replication factor A1.
  
 0.813
BAJ50661.1
DNA repair protein RadA; Involved in DNA repair and in homologous recombination. Binds and assemble on single-stranded DNA to form a nucleoprotein filament. Hydrolyzes ATP in a ssDNA-dependent manner and promotes DNA strand exchange between homologous DNA molecules.
 
 0.807
BAJ50804.1
Helicase-associated endonuclease for fork-structured DNA; ATP-dependent RNA helicase, eif-4a family.
  
 
 
 0.792
BAJ51254.1
Conserved hypothetical protein.
 
 0.788
BAJ50840.1
DNA repair exonuclease.
 
 0.786
BAJ50549.1
DNA repair protein RadB.
  
 0.782
Your Current Organism:
Caldiarchaeum subterraneum
NCBI taxonomy Id: 311458
Other names: C. Caldiarchaeum subterraneum, Candidatus Caldiarchaeum subterraneum, uncultured crenarchaeote 10-H-08
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.