Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
BAJ50226.12-methylthioadenine synthase. (432 aa)    
Predicted Functional Partners:
BAJ50225.1
Phosphoribosyltransferase.
  
    0.813
BAJ51428.1
Exosome complex component RRP4.
   
 
 0.782
rrp41
Exosome complex component RRP41; Catalytic component of the exosome, which is a complex involved in RNA degradation. Has 3'->5' exoribonuclease activity. Can also synthesize heteropolymeric RNA-tails.
 
   0.710
BAJ50566.1
Nitrite reductase (NO-forming).
       0.707
BAJ50366.1
Translation initiation factor eIF-2 beta subunit.
       0.700
BAJ50367.1
Conserved hypothetical protein.
       0.698
thiI
Thiamine biosynthesis protein ThiI; Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS.
  
  
 0.647
BAJ50223.1
Archaeal preflagellin peptidase FlaK.
       0.620
BAJ50870.1
ATP-binding protein involved in chromosome partitioning.
 
  
 0.617
BAJ51367.1
tRNA and rRNA cytosine-C5-methylases.
  
  
 0.614
Your Current Organism:
Caldiarchaeum subterraneum
NCBI taxonomy Id: 311458
Other names: C. Caldiarchaeum subterraneum, Candidatus Caldiarchaeum subterraneum, uncultured crenarchaeote 10-H-08
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