Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
BAJ50247.1F420-dependent N5,N10-methenyltetrahydromethanopterin reductase. (317 aa)    
Predicted Functional Partners:
BAJ51376.1
Coenzyme F420-dependent hydrogenase beta subunit.
 
 
 0.935
glyA
Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with a modified folate serving as the one-carbon carrier. Also exhibits a pteridine-independent aldolase activity toward beta- hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
    
 0.901
BAJ51479.1
Serine hydroxymethyltransferase.
    
 0.901
BAJ50248.1
Hypothetical protein.
       0.732
BAJ50098.1
Luciferase family protein.
  
     0.689
BAJ51088.1
LPPG:Fo 2-phospho-L-lactate transferase.
 
   
 0.563
BAJ51446.1
F420-0:gamma-glutamyl ligase.
 
   
 0.556
tuf
Elongation factor EF-1 alpha subunit; This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
       0.554
BAJ50246.1
3-octaprenyl-4-hydroxybenzoate carboxy-lyase.
       0.550
BAJ50244.1
Cobalt/nickel ABC transporter ATP-binding protein.
       0.512
Your Current Organism:
Caldiarchaeum subterraneum
NCBI taxonomy Id: 311458
Other names: C. Caldiarchaeum subterraneum, Candidatus Caldiarchaeum subterraneum, uncultured crenarchaeote 10-H-08
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