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Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
BAJ50285.1Mevalonate kinase. (319 aa)    
Predicted Functional Partners:
BAJ50369.1
3-hydroxy-3-methylglutaryl-CoA reductase; Belongs to the HMG-CoA reductase family.
 0.998
BAJ51480.1
Diphosphomevalonate decarboxylase.
 
 
 0.997
fni
Isopentenyl-diphosphate delta-isomerase; Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP).
 
  
 0.960
BAJ50286.1
Acetylglutamate kinase.
     
 0.941
BAJ50447.1
Octaprenyl-diphosphate synthase; Belongs to the FPP/GGPP synthase family.
  
  
 0.880
BAJ50284.1
Conserved hypothetical protein; Memo-like protein; Belongs to the MEMO1 family.
 
     0.877
BAJ51320.1
Conserved hypothetical protein; 3-oxoacyl-[acyl-carrier-protein (ACP); Belongs to the thiolase-like superfamily. UPF0219 family.
 
  
 0.859
rpoN
DNA-directed RNA polymerase subunit N; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal RpoN/eukaryotic RPB10 RNA polymerase subunit family.
       0.846
BAJ50283.1
Dihydropyrimidinase.
       0.773
gltX
glutamyl-tRNA synthetase; Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
  
    0.727
Your Current Organism:
Caldiarchaeum subterraneum
NCBI taxonomy Id: 311458
Other names: C. Caldiarchaeum subterraneum, Candidatus Caldiarchaeum subterraneum, uncultured crenarchaeote 10-H-08
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