Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
BAJ50297.1Conserved hypothetical protein; Catalyzes the GTP-dependent phosphorylation of the 3'- hydroxyl group of dephosphocoenzyme A to form coenzyme A (CoA). (168 aa)    
Predicted Functional Partners:
BAJ50295.1
DNA-directed RNA polymerase subunit E'.
 
    0.971
BAJ50299.1
Small subunit ribosomal protein S24e.
  
  
 0.953
BAJ50627.1
Phosphopantetheine adenylyltransferase.
  
  
 0.930
spt4
DNA-directed RNA polymerase subunit E; Stimulates transcription elongation; Belongs to the archaeal Spt4 family.
 
    0.917
rps6e
Small subunit ribosomal protein S6e; Belongs to the eukaryotic ribosomal protein eS6 family.
 
    0.894
BAJ50293.1
Translation initiation factor eIF-2 gamma subunit.
 
    0.864
rps27ae
Small subunit ribosomal protein S27Ae; Belongs to the eukaryotic ribosomal protein eS31 family.
 
  
 0.831
BAJ50294.1
Conserved hypothetical protein.
       0.829
BAJ50304.1
Nucleoside-triphosphatase; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family.
 
     0.780
kae1
O-sialoglycoprotein endopeptidase; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37; Belongs to the KAE1 / TsaD family.
       0.700
Your Current Organism:
Caldiarchaeum subterraneum
NCBI taxonomy Id: 311458
Other names: C. Caldiarchaeum subterraneum, Candidatus Caldiarchaeum subterraneum, uncultured crenarchaeote 10-H-08
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