Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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textmining
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experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
BAJ50303.1Mn2+-dependent serine/threonine protein kinase. (214 aa)    
Predicted Functional Partners:
kae1
O-sialoglycoprotein endopeptidase; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37; Belongs to the KAE1 / TsaD family.
   
 0.995
rps15
Small subunit ribosomal protein S15.
 
   
 0.939
BAJ50304.1
Nucleoside-triphosphatase; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family.
 
   
 0.901
BAJ51100.1
Conserved hypothetical protein.
    
 
 0.895
BAJ50306.1
Archaea-specific RecJ-like exonuclease.
 
     0.877
BAJ50299.1
Small subunit ribosomal protein S24e.
  
    0.870
rps6e
Small subunit ribosomal protein S6e; Belongs to the eukaryotic ribosomal protein eS6 family.
 
     0.816
rps27ae
Small subunit ribosomal protein S27Ae; Belongs to the eukaryotic ribosomal protein eS31 family.
       0.799
BAJ50307.1
Hypothetical protein.
       0.798
rps3ae
Small subunit ribosomal protein S3Ae; Belongs to the eukaryotic ribosomal protein eS1 family.
 
     0.793
Your Current Organism:
Caldiarchaeum subterraneum
NCBI taxonomy Id: 311458
Other names: C. Caldiarchaeum subterraneum, Candidatus Caldiarchaeum subterraneum, uncultured crenarchaeote 10-H-08
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