STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
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Co-occurrence
Co-expression
Experiments
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[Homology]
Score
ahcYAdenosylhomocysteinase; May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine. (435 aa)    
Predicted Functional Partners:
BAJ50320.1
5-methyltetrahydropteroyltriglutamate-- homocysteine methyltransferase.
  
 
 0.968
BAJ50321.1
Methylcobalamin:homocysteine methyltransferase.
  
 
 0.968
BAJ51573.1
Cysteine synthase A.
  
 0.880
BAJ51032.1
Homoserine dehydrogenase.
  
 
 0.832
BAJ49970.1
Threonine dehydratase.
  
 
 0.831
thrB
Homoserine kinase; Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate; Belongs to the GHMP kinase family. Homoserine kinase subfamily.
  
 
  0.819
BAJ50364.1
Hypothetical protein.
     
 0.780
fusA
Elongation factor EF-2; Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.
  
 
 0.705
BAJ50821.1
Hypothetical protein; Similar to N-terminal of 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase.
  
  
 0.694
BAJ50366.1
Translation initiation factor eIF-2 beta subunit.
  
 
 0.639
Your Current Organism:
Caldiarchaeum subterraneum
NCBI taxonomy Id: 311458
Other names: C. Caldiarchaeum subterraneum, Candidatus Caldiarchaeum subterraneum, uncultured crenarchaeote 10-H-08
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.