Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
BAJ50400.1Conserved hypothetical protein; Involved in DNA damage repair. (410 aa)    
Predicted Functional Partners:
BAJ50401.1
ATPase.
 
     0.799
BAJ50587.1
Archaeal cell division control protein 6; Involved in regulation of DNA replication.
  
     0.638
BAJ50323.1
Phosphate uptake regulator.
 
     0.637
nac
Nascent polypeptide-associated complex subunit alpha; Contacts the emerging nascent chain on the ribosome. Belongs to the NAC-alpha family.
  
     0.626
BAJ50993.1
Phosphate uptake regulator.
 
     0.616
BAJ51008.1
Phosphate regulatory protein.
 
     0.616
BAJ50306.1
Archaea-specific RecJ-like exonuclease.
  
     0.603
BAJ50043.1
Conserved hypothetical protein.
 
     0.591
priS
DNA primase small subunit; Catalytic subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. The small subunit contains the primase catalytic core and has DNA synthesis activity on its own. Binding to the large subunit stabilizes and modulates the activity, increasing the rate of DNA synthesis while decreasing the length of the DNA fragments, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synthesis. [...]
 
     0.587
nusA
N utilization substance protein A; Participates in transcription termination. Belongs to the NusA family.
  
     0.586
Your Current Organism:
Caldiarchaeum subterraneum
NCBI taxonomy Id: 311458
Other names: C. Caldiarchaeum subterraneum, Candidatus Caldiarchaeum subterraneum, uncultured crenarchaeote 10-H-08
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